User profiles for R. B. Fletcher

Brock Fletcher

NSF Graduate Research Fellow, Vanderbilt University
Verified email at vanderbilt.edu
Cited by 185

[HTML][HTML] Slingshot: cell lineage and pseudotime inference for single-cell transcriptomics

K Street, D Risso, RB Fletcher, D Das, J Ngai, N Yosef… - BMC genomics, 2018 - Springer
Background Single-cell transcriptomics allows researchers to investigate complex communities
of heterogeneous cells. It can be applied to stem cells and their descendants in order to …

Non-neuronal expression of SARS-CoV-2 entry genes in the olfactory system suggests mechanisms underlying COVID-19-associated anosmia

…, R Chance, IC Macaulay, HJ Chou, RB Fletcher… - Science …, 2020 - science.org
Altered olfactory function is a common symptom of COVID-19, but its etiology is unknown. A
key question is whether SARS-CoV-2 (CoV-2) – the causal agent in COVID-19 – affects …

Neural crest induction by paraxial mesoderm in Xenopus embryos requires FGF signals

AH Monsoro-Burq, RB Fletcher, RM Harland - 2003 - journals.biologists.com
At the border of the neural plate, the induction of the neural crest can be achieved by interactions
with the epidermis, or with the underlying mesoderm. Wnt signals are required for the …

Faculty and students conceptions of assessment in higher education

RB Fletcher, LH Meyer, H Anderson, P Johnston… - Higher education, 2012 - Springer
Assessment in higher education serves multiple purposes such as providing information
about student learning, student progress, teaching quality, and program and institutional …

[PDF][PDF] Deconstructing olfactory stem cell trajectories at single-cell resolution

RB Fletcher, D Das, L Gadye, KN Street, A Baudhuin… - Cell stem cell, 2017 - cell.com
A detailed understanding of the paths that stem cells traverse to generate mature progeny is
vital for elucidating the mechanisms governing cell fate decisions and tissue homeostasis. …

[PDF][PDF] p63 regulates olfactory stem cell self-renewal and differentiation

RB Fletcher, MS Prasol, J Estrada, A Baudhuin… - Neuron, 2011 - cell.com
The olfactory epithelium is a sensory neuroepithelium that supports adult neurogenesis and
tissue regeneration following injury, making it an excellent model for investigating neural …

FGF8 spliceforms mediate early mesoderm and posterior neural tissue formation in Xenopus

RB Fletcher, JC Baker, RM Harland - 2006 - journals.biologists.com
The relative contributions of different FGF ligands and spliceforms to mesodermal and neural
patterning in Xenopus have not been determined,and alternative splicing, though common, …

The Group Environment Questionnaire: A multilevel confirmatory factor analysis

SM Whitton, RB Fletcher - Small Group Research, 2014 - journals.sagepub.com
Fletcher is senior lecturer in research methods in the School of Psychology at Massey
University in Auckland, New Zealand. His research focuses of methodological applications within …

The role of FGF signaling in the establishment and maintenance of mesodermal gene expression in Xenopus

RB Fletcher, RM Harland - Developmental dynamics: an official …, 2008 - Wiley Online Library
FGF signaling is important for the formation of mesoderm in vertebrates, and when it is perturbed
in Xenopus, most trunk and tail mesoderm fails to form. Here we have further dissected …

[HTML][HTML] An anionic, endosome-escaping polymer to potentiate intracellular delivery of cationic peptides, biomacromolecules, and nanoparticles

BC Evans, RB Fletcher, KV Kilchrist, EA Dailing… - Nature …, 2019 - nature.com
Peptides and biologics provide unique opportunities to modulate intracellular targets not
druggable by conventional small molecules. Most peptides and biologics are fused with …