Motivation: Gene expression microarray experiments can generate data sets with multiple
missing expression values. Unfortunately, many algorithms for gene expression analysis …

The Pharmacogenomics Knowledgebase (PharmGKB) is a resource that collects, curates,
and disseminates information about the impact of human genetic variation on drug responses. …

The goal of this study is to give a brief background on the literature supporting the PharmGKB
pathway about doxorubicin action, and provides a summary of this active area of research. …

The global gene expression profiles for 67 human lung tumors representing 56 patients were
examined by using 24,000-element cDNA microarrays. Subdivision of the tumors based on …

The discovery of rare genetic variants is accelerating, and clear guidelines for distinguishing
disease-causing sequence variants from the many potentially functional variants present in …

Personalized medicine is expected to benefit from combining genomic information with regular
monitoring of physiological states by multiple high-throughput methods. Here, we present …

A series of microarray experiments produces observations of differential expression for
thousands of genes across multiple conditions. It is often not clear whether a set of experiments …

Genetics aims to understand the relation between genotype and phenotype. However,
because complete deletion of most yeast genes (∼80%) has no obvious phenotypic …

Lung cancer is the most prevalent cancer worldwide, and histopathological assessment is
indispensable for its diagnosis. However, human evaluation of pathology slides cannot …

… Rensi and Altman developed a method for computing the similarity of chemical transformations
using Tanimoto kernel embedded fingerprints and extended a fuzzy search capability to …