RSK regulates activated BRAF signalling to mTORC1 and promotes melanoma growth

Y Romeo, J Moreau, PJ Zindy, M Saba-El-Leil… - Oncogene, 2013 - nature.com
The Ras/mitogen-activated protein kinase (MAPK) signalling cascade regulates various
biological functions, including cell growth, proliferation and survival. As such, this pathway is …

Formation of the eIF4F translation–initiation complex determines sensitivity to anticancer drugs targeting the EGFR and HER2 receptors

P Zindy, Y Bergé, B Allal, T Filleron, S Pierredon… - Cancer research, 2011 - AACR
… The ratio of polysome distribution (P/cyto.) in “polysome” (P) fraction versus total cytoplasmic
extract (cyto.) in trastuzumab-… P. Zindy was supported by an FRM postdoctoral fellowship. …

Nol12 is a multifunctional RNA binding protein at the nexus of RNA and DNA metabolism

DD Scott, C Trahan, PJ Zindy, LC Aguilar… - Nucleic acids …, 2017 - academic.oup.com
To counteract the breakdown of genome integrity, eukaryotic cells have developed a
network of surveillance pathways to prevent and resolve DNA damage. Recent data has …

[HTML][HTML] MIR@ NT@ N: a framework integrating transcription factors, microRNAs and their targets to identify sub-network motifs in a meta-regulation network model

…, E Portales-Casamar, G Vetter, M Moes, PJ Zindy… - BMC …, 2011 - Springer
p-values for a common reference DNA sequence (see "Motif Scoring Procedure and
Computation of JASPAR Profile Matrix Score p-… to a p-value no more permissive than p < 0.01. …

Responses to increased moisture stress and extremes: whole plant response to drought under climate change

…, J Kholova, S Choudhary, P Zindy… - Crop adaptation to …, 2011 - Wiley Online Library
Research on adaptation of crops to drought has received considerable attention over the
past century. With the current and predicted increases in temperature and likely decreases in …

[PDF][PDF] Upregulation of the tumor suppressor gene menin in hepatocellular carcinomas and its significance in fibrogenesis

PJ Zindy, A L'Helgoualc'h, D Bonnier, A Le Béchec… - …, 2006 - Wiley Online Library
… in tumor was confirmed in an independent set of samples and associated with tumor size (P
… Pierre Zindy was a recipient of a fellowship from the Association pour la Recherche contre …

Component traits of plant water use are modulated by vapour pressure deficit in pearl millet (Pennisetum glaucum (L.) R. Br.)

J Kholová, P Zindy, S Malayee, R Baddam… - Functional Plant …, 2016 - CSIRO Publishing
… , and these normalised values were used in the ANOVA at P ≤ 0.05. In this way, regardless
of … For the root cell parameters, Pearson’s correlation coefficient and the P-level up to P < 0.1 …

[HTML][HTML] Hepatocyte iron loading capacity is associated with differentiation and repression of motility in the HepaRG cell line

…, P Zindy, P Leroyer, I Guisle, H Duval, P Gripon… - Genomics, 2006 - Elsevier
… A color code is given for the statistical p-value of enrichment calculation (p < 0.01 in
sweet colour, p < 0.001 in hard color, blue for non significant enrichment). An arrow code is …

[HTML][HTML] Upregulation of DNA repair genes in active cirrhosis associated with hepatocellular carcinoma

P Zindy, L Andrieux, D Bonnier, O Musso, S Langouët… - FEBS letters, 2005 - Elsevier
… The upregulation of DNA repair genes was confirmed by real-time quantitative polymerase
chain reaction and associated with necroinflammatory activity (P<0.001). Increased DNA …

M@ IA: a modular open-source application for microarray workflow and integrative datamining

A Le Béchec, P Zindy, T Sierocinski, D Pétritis… - In silico …, 2008 - content.iospress.com
… Gene Ontology terms and KEGG pathways can be filtered by the P-value of the Fisher’s test
and by the number of associated genes. When gene regulation (Up or Down) is included in …