We sequenced the genomes of a ∼7,000-year-old farmer from Germany and eight ∼8,000-year-old
hunter-gatherers from Luxembourg and Sweden. We analysed these and other …

Genome-wide association studies (GWAS) in coronary artery disease (CAD) had identified
66 loci at'genome-wide significance'(P< 5× 10− 8) at the time of this analysis, but a much …

The nonrecombining portion of the human Y chromosome has proven to be a valuable tool
for the study of population history. The maintenance of extended haplotypes characteristic of …

The discovery of genetic loci associated with complex diseases has outpaced the elucidation
of mechanisms of disease pathogenesis. Here we conducted a genome-wide association …

North African populations are distinct from sub-Saharan Africans based on cultural, linguistic,
and phenotypic attributes; however, the time and the extent of genetic divergence between …

Background The nature and underlying mechanisms of an inverse association between
adult height and the risk of coronary artery disease (CAD) are unclear. Methods We used a …

We analyzed 40 single nucleotide polymorphism and 19 short tandem repeat Y-chromosomal
markers in a large sample of 1,525 indigenous individuals from 14 populations in the …

… number of cycles of fertility treatment for case–control studies (P = 0.045), while no significant
trend was observed for cohort studies (P = 0.276) nor for all combined studies (P = 0.069). …

The predominantly African origin of all modern human populations is well established, but
the route taken out of Africa is still unclear. Two alternative routes, via Egypt and Sinai or …

Background Between 2011 and 2013, the Lebanese population increased by 30% due to
the influx of Syrian refugees. While a sudden increase of such magnitude represents a shock …