Given that cardiovascular safety liabilities remain a major cause of drug attrition during
preclinical and clinical development, adverse drug reactions, and post‐approval withdrawal of …

1. Introduction(electrical heterogeneity with nonuniform repolarization and refractoriness)
for the initiation and perpetuation of Afterdepolarizations are oscillations of the transmem- …

… Paul GA Volders Paul GA Volders … Tereshchenko, Paul GA Volders, QT interval variability
in body surface ECG: measurement, physiological basis, and clinical value: position statement …

… The Randfold algorithm implements the randomization test and returns the mean free
energy of folding and P-value for every RNA sequence. Hence, a significant P-value denotes a …

Background— Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) is a
progressive cardiomyopathy. We aimed to define long-term outcome in a transatlantic cohort of …

While long non-coding RNA (lncRNA) research in the past has primarily focused on the
discovery of novel genes, today it has shifted towards functional annotation of this large class of …

… Footprint alignments were assigned to a specific P-site nucleotide based on the fragment
length (the 5′ offset is set to respectively 12, 13 or 14 for profiles with length ≤ 30 nt, 31–33 nt…

… No correlations were identified between RR plot areas and QT or LV plot areas (P=0.7 and
0.4, respectively). Table 2 shows that the accuracy of individual predictions in the present …

… the extent of shortening (P=NS, Figure 1). In cells from CAVB dogs, the extent of shortening
was significantly larger than in controls at frequencies <120 bpm (P<0.05) and tended to …

… P<0.05 isoproterenol vs baseline; #P<0.05 isoproterenol vs isoproterenol plus I Ks blocker.
… P<0.05 isoproterenol vs baseline; #P<0.05 isoproterenol vs isoproterenol plus I Ks blocker. …