User profiles for P. Turley

Patrick Turley

Assistant Professor (Research), University of Southern California
Verified email at broadinstitute.org
Cited by 17328

Analysis of shared heritability in common disorders of the brain

…, S Ripke, Z Wei, D Yu, PH Lee, P Turley… - Science, 2018 - science.org
INTRODUCTION Brain disorders may exhibit shared symptoms and substantial epidemiological
comorbidity, inciting debate about their etiologic overlap. However, detailed study of …

Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder

…, FK Satterstrom, H Stefansson, C Stevens, P Turley… - Nature …, 2019 - nature.com
Attention deficit/hyperactivity disorder (ADHD) is a highly heritable childhood behavioral
disorder affecting 5% of children and 2.5% of adults. Common genetic variants contribute …

Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals

…, J Yang, M Johannesson, PD Koellinger, P Turley… - Nature …, 2018 - nature.com
Here we conducted a large-scale genetic association analysis of educational attainment in
a sample of approximately 1.1 million individuals and identify 1,271 independent genome-…

Identification of common genetic risk variants for autism spectrum disorder

…, S Steinberg, CR Stevens, PF Sullivan, P Turley… - Nature …, 2019 - nature.com
Autism spectrum disorder (ASD) is a highly heritable and heterogeneous group of
neurodevelopmental phenotypes diagnosed in more than 1% of children. Common genetic variants …

[HTML][HTML] Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals

…, JJ Lee, A Kong, L Yengo, D Cesarini, P Turley… - Nature …, 2022 - nature.com
We conduct a genome-wide association study (GWAS) of educational attainment (EA) in a
sample of~ 3 million individuals and identify 3,952 approximately uncorrelated genome-wide-…

Genome-wide association study identifies 74 loci associated with educational attainment

…, MA Fontana, JJ Lee, TH Pers, CA Rietveld, P Turley… - Nature, 2016 - nature.com
Educational attainment is strongly influenced by social and other environmental factors, but
genetic factors are estimated to account for at least 20% of the variation across individuals 1. …

FDM® Technology process improvements

J Comb, W Priedeman, PW Turley - 1994 - repositories.lib.utexas.edu
Since the introduction ofrapid prototyping technology as a tool for time compression and
concurrent engineering in the design and manufacturing process, many enhancements and …

Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses

A Okbay, BML Baselmans, JE De Neve, P Turley… - Nature …, 2016 - nature.com
Very few genetic variants have been associated with depression and neuroticism, likely
because of limitations on sample size in previous studies. Subjective well-being, a phenotype …

Managing the developing Class III malocclusion with palatal expansion and facemask therapy

PK Turley - American Journal of Orthodontics and Dentofacial …, 2002 - Elsevier
One of the most significant changes in the area of early treatment in recent decades concerns
managing the developing Class III malocclusion. Twenty-five years ago, early intervention …

[PDF][PDF] Genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders

…, MS Artigas, S Steinberg, H Stefansson, P Turley… - Cell, 2019 - cell.com
Genetic influences on psychiatric disorders transcend diagnostic boundaries, suggesting
substantial pleiotropy of contributing loci. However, the nature and mechanisms of these …