Tumor infarction in mice by antibody-directed targeting of tissue factor to tumor vasculature
…, S King, L Watkins, TS Edgington, PE Thorpe - Science, 1997 - science.org
… These antitumor effects were significantly greater than for all other treatment groups (P < …
Two-tailed P values are for differences in tumor volume (day 14) by the Mann-Whitney rank sum …
Two-tailed P values are for differences in tumor volume (day 14) by the Mann-Whitney rank sum …
Vascular targeting agents as cancer therapeutics
PE Thorpe - Clinical Cancer Research, 2004 - AACR
… Ran, S., and Thorpe, PE Antibodies to anionic phospholipids as vascular targeting agents
for cancer treatment. Abstract 12 presented at Angiogenesis 2 Meeting, Paris, June 19–20, …
for cancer treatment. Abstract 12 presented at Angiogenesis 2 Meeting, Paris, June 19–20, …
Is percutaneous drainage the new gold standard in the management of emphysematous pyelonephritis? Evidence from a systematic review
PURPOSE: There is no current consensus on what constitutes the ideal management of
emphysematous pyelonephritis. We review the current management strategies including the …
emphysematous pyelonephritis. We review the current management strategies including the …
Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis
…, TH Vu, T Itoh, K Tamaki, K Tanzawa, P Thorpe… - Nature cell …, 2000 - nature.com
During carcinogenesis of pancreatic islets in transgenic mice, an angiogenic switch activates
the quiescent vasculature. Paradoxically, vascular endothelial growth factor (VEGF) and its …
the quiescent vasculature. Paradoxically, vascular endothelial growth factor (VEGF) and its …
Integrated screening validates primary axes of specialisation in plants
…, RE Spencer, F Sutton, DE Tasker, PC Thorpe… - Oikos, 1997 - JSTOR
Standardised procedures have been used to measure 67 traits in 43 common plants of the
British flora. This paper provides an interpretation of the most consistent patterns in the …
British flora. This paper provides an interpretation of the most consistent patterns in the …
Increased exposure of anionic phospholipids on the surface of tumor blood vessels
S Ran, A Downes, PE Thorpe - Cancer research, 2002 - AACR
… Burrows FJ, Watanabe Y., Thorpe PE A murine model for antibody-directed targeting of …
Ran S., Downes A., Thorpe PE Increased exposure of anionic phospholipids on the surface of …
Ran S., Downes A., Thorpe PE Increased exposure of anionic phospholipids on the surface of …
The antimicrobial properties of chile peppers (Capsicum species) and their uses in Mayan medicine
RH Cichewicz, PA Thorpe - Journal of ethnopharmacology, 1996 - Elsevier
A survey of the Mayan pharmacopoeia revealed that tissues of Capsicum species (Solanaceae)
are included in a number of herbal remedies for a variety of ailments of probable …
are included in a number of herbal remedies for a variety of ailments of probable …
Up-regulation of endoglin on vascular endothelial cells in human solid tumors: implications for diagnosis and therapy.
…, SW King, M Letarte, ES Vitetta, PE Thorpe - Clinical cancer research …, 1995 - AACR
We have characterized a murine IgM monoclonal antibody, TEC-11, that recognizes endoglin
and may be suitable for targeting cytotoxic agents to human tumor vasculature. TEC-11 …
and may be suitable for targeting cytotoxic agents to human tumor vasculature. TEC-11 …
Selective inhibition of vascular endothelial growth factor (VEGF) receptor 2 (KDR/Flk-1) activity by a monoclonal anti-VEGF antibody blocks tumor growth in mice
…, VA Stastny, J Waltenberger, JD Minna, PE Thorpe - Cancer research, 2000 - AACR
Vascular endothelial growth factor (VEGF) is a multifunctional angiogenic growth factor that
is a primary stimulant of the development and maintenance of a vascular network in …
is a primary stimulant of the development and maintenance of a vascular network in …
Soluble Eph A receptors inhibit tumor angiogenesis and progression in vivo
…, EJ Thompson, Q Lin, RA Brekken, PE Thorpe… - Oncogene, 2002 - nature.com
The Eph family of receptor tyrosine kinases and their ligands, known as ephrins, play a crucial
role in vascular development during embryogenesis. The function of these molecules in …
role in vascular development during embryogenesis. The function of these molecules in …