… binding of paclitaxel increased 9.9-fold (P < 0.0001) and transport of paclitaxel across the
endothelial cell monolayer increased 4.2-fold (P < 0.0001) with nab-paclitaxel compared with …

The identification of extensive genetic heterogeneity in human breast carcinomas poses a
significant challenge for designing effective treatment regimens. Significant genomic evolution …

… The ABI007 group showed a trend toward slower tumor growth group (P = 0.06) and
longer median tumor doubling times (44.9 and 29.4 days for ABI-007 and Cremophor-based …

… sex, race, age, treatment, and baseline CA19-9 level (P = .041). Additionally, stromal
SPARC was significantly correlated with OS (P = .013), but not SPARC in tumor cells (P = .15). …

Purpose: ABI-007 is a novel Cremophor-free, protein-stabilized, nanoparticle formulation of
paclitaxel. The absence of Cremophor EL may permit ABI-007 to be administered without the …

Immune rejection following transplantation of non-encapsulated pancreatic islets has
remained a major obstacle to successful treatment of type I diabetes, despite the use of high-dose …

Identification of a biocompatible immunoprotective membrane to prevent graft rejection remained
elusive until the development of microcapsules formulated in alginate high in guluronic …

The interactions between alginate and polycations have been studied by using different
labelling techniques. Binding of poly-l-lysine (PLL) to alginate in the gel state is mainly governed …

Alginates are polysaccharides with gel-forming properties composed of 1, 4-linked [beta]-D-mannuronic
acid (M),[alpha]-L-guluronic acid (G), and alternating (MG) blocks. Alginate can …

… vs 59.84 months for SPARC-negative patients; P = .018). The association of SPARC status
with DFI and OS was even more significant (P < .001) when analyzed in combination with PAI-…