The neuropathological hallmark of Parkinson’s disease is the loss of dopaminergic neurons
in the substantia nigra pars compacta, presumably mediated by apoptosis. The homeobox …

The homeobox transcription factors Engrailed-1 and Engrailed-2 are required for the
survival of mesencephalic dopaminergic neurons in a cell-autonomous and gene-dose-dependent …

The homeobox-containing transcription factor Engrailed-2 (En2) is involved in patterning and
neuronal differentiation of the midbrain/hindbrain region, where it is prominently expressed…

… Statistical analysis performed by two-way repeated measures ANOVA revealed a significant
effect of genotype (F 1,136 =7.522, P=0.014). Multiple comparison procedure showed that …

Biological predispositions to attend to visual cues, such as those associated with face-like
stimuli or with biological motion, guide social behavior from the first moments of life and have …

Autism spectrum disorders (ASD) and epilepsy are very common neurological disorders of
childhood, with an estimated incidence of about 0.5–1% in worldwide population. ASD and …

… We obtained a Pearson’s correlation of 1.000, p < 0.001 between the preference scores
calculated using our original data and the blind coding. For the present study 51 VPA-injected (…

Faces convey a great amount of socially relevant information related to emotional and mental
states, identity and intention. Processing of face information is a key mechanism for social …

… test, p = 0.04 for vGAT and p = 0.008 for NPY; n = 4 per genotype) (Figures 1F,G). They
significantly decreased in En2 −/− mice from P30 to the adult age (vGAT, −25%; NPY, −42%; Two-…

… All shown p-values are rounded up at the third or fourth digit. … increases the survival rate
of En DM mesDA neurons (n ≥ 6; p < 0.001), whereas nerve growth factor (NGF), glial cell line-…