User profiles for P. Schaap

PJ Schaap

Associate professor, Systems and Synthetic Biology, Wageningen University, The …
Verified email at wur.nl
Cited by 8862

Evolutionary crossroads in developmental biology: Dictyostelium discoideum

P Schaap - Development, 2011 - journals.biologists.com
… , 1979; Traynor et al., 1992) by reducing their expression of certain proteins, such as
cAR1 and PdsA, that are essential for generating and sensing steep chemotactic gradients (Schaap

Signal transduction of bone morphogenetic proteins in osteoblast differentiation

P Ten Dijke, J Fu, P Schaap, BAJ Roelen - JBJS, 2003 - journals.lww.com
BY PETER TEN DIJKE, PHD, JINGYUAN FU, MS, PETER SCHAAP, PHD, AND BERNARD
AJ ROELEN, PHD one morphogenetic proteins (BMPs) were initially identified by their ability …

[HTML][HTML] Genome sequencing and analysis of the versatile cell factory Aspergillus niger CBS 513.88

…, DB Archer, PS Dyer, G Hofmann, PJ Schaap… - Nature …, 2007 - nature.com
The filamentous fungus Aspergillus niger is widely exploited by the fermentation industry for
the production of enzymes and organic acids, particularly citric acid. We sequenced the 33.9-…

[HTML][HTML] A genomic view on syntrophic versus non-syntrophic lifestyle in anaerobic fatty acid degrading communities

…, M Visser, VT Sedano-Núñez, PJ Schaap… - … et Biophysica Acta (BBA …, 2014 - Elsevier
… The domain “IPR020539” that seems exclusively present in syntrophs in our analysis
belongs to the protein Ribonuclease P which removes extra residues at the 5′-side from …

Comparative genomics of citric-acid-producing Aspergillus niger ATCC 1015 versus enzyme-producing CBS 513.88

MR Andersen, MP Salazar, PJ Schaap… - Genome …, 2011 - genome.cshlp.org
The filamentous fungus Aspergillus niger exhibits great diversity in its phenotype. It is found
globally, both as marine and terrestrial strains, produces both organic acids and hydrolytic …

[HTML][HTML] Genome of Acanthamoeba castellanii highlights extensive lateral gene transfer and early evolution of tyrosine kinase signaling

…, N Chen, P Nash, ML Ginger, M Horn, P Schaap… - Genome biology, 2013 - Springer
Background The Amoebozoa constitute one of the primary divisions of eukaryotes, encompassing
taxa of both biomedical and evolutionary importance, yet its genomic diversity remains …

MEMOTE for standardized genome-scale metabolic model testing

…, A Richelle, I Rocha, BJ Sánchez, PJ Schaap… - Nature …, 2020 - nature.com
To the Editor—Reconstructing metabolic reaction networks enables the development of
testable hypotheses of an organism’s metabolism under different conditions 1. State-of-the-art …

[PDF][PDF] RNA targeting by the type III-A CRISPR-Cas Csm complex of Thermus thermophilus

…, T Suzuki, N Dohmae, S Yokoyama, PJ Schaap… - Molecular cell, 2014 - cell.com
CRISPR-Cas is a prokaryotic adaptive immune system that provides sequence-specific
defense against foreign nucleic acids. Here we report the structure and function of the effector …

Molecular phylogeny and evolution of morphology in the social amoebas

P Schaap, T Winckler, M Nelson, E Alvarez-Curto… - Science, 2006 - science.org
The social amoebas (Dictyostelia) display conditional multicellularity in a wide variety of
forms. Despite widespread interest in Dictyostelium discoideum as a model system, almost no …

[PDF][PDF] Structure and activity of the RNA-targeting Type III-B CRISPR-Cas complex of Thermus thermophilus

…, K Sakamoto, A Masuda, N Dohmae, PJ Schaap… - Molecular cell, 2013 - cell.com
The CRISPR-Cas system is a prokaryotic host defense system against genetic elements. The
Type III-B CRISPR-Cas system of the bacterium Thermus thermophilus, the TtCmr complex…