Neurochemokines: a menage a trois providing new insights on the functions of chemokines in the central nervous system

…, E Apartis, S Hunot, N Beaudet, P Sarret - Journal of …, 2011 - Wiley Online Library
… (a) In the dorsal root ganglia (DRG), CCL2 co-localizes in large dense-core vesicles with
classical nociceptive peptidergic neuromediators such as substance P. (b) Superfusion …

Glial and neuroimmune cell choreography in sexually dimorphic pain signaling

É Midavaine, J Côté, S Marchand, P Sarret - Neuroscience & Biobehavioral …, 2021 - Elsevier
Chronic pain is a major global health issue that affects all populations regardless of sex, age,
ethnicity/race, or country of origin, leading to persistent physical and emotional distress …

Chemokine network in the nervous system: a new target for pain relief

…, M Pohl, P Kitabgi, N Beaudet, P Sarret… - Current medicinal …, 2008 - ingentaconnect.com
Physical insults including but not limited to nerve damage, inflammation, visceral pathologies
and cancer generate long lasting pain commonly referred as chronic pain. Recently, …

Structure, functional expression, and cerebral localization of the levocabastine-sensitive neurotensin/neuromedin N receptor from mouse brain

…, E Guillemare, T Coppola, P Sarret… - Journal of …, 1996 - Soc Neuroscience
… a template to produce sense and antisense 33 P-labeled RNA probes. Paraformaldehyde-…
sulfate, and 0.6% sarcosyl with antisense and sense 33 P-labeled RNA probes (3 × 10 5 cpm/…

CCL2 released from neuronal synaptic vesicles in the spinal cord is a major mediator of local inflammation and pain after peripheral nerve injury

…, MA Dansereau, P Kitabgi, P Sarret… - Journal of …, 2011 - Soc Neuroscience
… with rabbit polyclonal anti-p-p44/42 mitogen-activated protein kinase (MAPK) (p-p44/42
MAPK or p-ERK1/2) or rabbit polyclonal anti-p-AKT or rabbit polyclonal anti-p-p38 antibodies (1:…

Spinal CCL2 pronociceptive action is no longer effective in CCR2 receptor antagonist‐treated rats

…, P Kitabgi, N Beaudet, P Sarret… - Journal of …, 2008 - Wiley Online Library
… a threshold of significance of p < 0.05, p < 0.01 and p < 0.001. Statistics were performed
using a statistical software package (SigmaStat version 2.03, Jandel Sci, San Rafael CA, USA). …

Increased anxiety-like behaviors in rats experiencing chronic inflammatory pain

…, J Bergeron, P Bérubé, G Drolet, P Sarret… - Behavioural brain …, 2012 - Elsevier
… A P-value <0.05 was considered statistically significant. … significant differences from
saline-injected animals; *P < 0.05. … differences from saline-injected animals; **P < 0.01 and *P < …

[HTML][HTML] Combination of high-fat/high-fructose diet and low-dose streptozotocin to model long-term type-2 diabetes complications

…, JM Longpré, AC Carpentier, P Geraldes, P Sarret - Scientific Reports, 2018 - nature.com
The epidemic of type 2 diabetes mellitus (T2DM) is fueled by added fructose consumption.
Here, we thus combined high-fat/high-fructose diet, with multiple low-dose injections of …

Discovery and structure–activity relationship of a bioactive fragment of ELABELA that modulates vascular and cardiac functions

…, O Lesur, M Auger-Messier, P Sarret… - Journal of medicinal …, 2016 - ACS Publications
ELABELA (ELA) was recently discovered as a novel endogenous ligand of the apelin receptor
(APJ), a G protein-coupled receptor. ELA signaling was demonstrated to be crucial for …

Distribution of NTS3 receptor/sortilin mRNA and protein in the rat central nervous system

P Sarret, P Krzywkowski, L Segal… - Journal of …, 2003 - Wiley Online Library
… Philippe Sarret and Pascale Krzywkowski contributed … Philippe Sarret and Pascale
Krzywkowski contributed equally to … Philippe Sarret and Pascale Krzywkowski contributed equally …