Activation and function of the MAPKs and their substrates, the MAPK-activated protein kinases
M Cargnello, PP Roux - Microbiology and molecular biology …, 2011 - Am Soc Microbiol
The mitogen-activated protein kinases (MAPKs) regulate diverse cellular programs by relaying
extracellular signals to intracellular responses. In mammals, there are more than a dozen …
extracellular signals to intracellular responses. In mammals, there are more than a dozen …
ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions
… (159), and alanine substitution of Pro364 only slightly reduces mitogen-stimulated RSK1
activation (P. Roux, unpublished results), suggesting that another kinase that does not require a …
activation (P. Roux, unpublished results), suggesting that another kinase that does not require a …
Neurotrophin signaling through the p75 neurotrophin receptor
The neurotrophins are growth factors that play critical roles in the development, maintenance,
survival, and death of the nervous system. The signal transducing systems that mediate …
survival, and death of the nervous system. The signal transducing systems that mediate …
[HTML][HTML] Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb
Background: Tuberous Sclerosis Complex (TSC) is a genetic disorder that occurs through
the loss of heterozygosity of either TSC1 or TSC2, which encode Hamartin or Tuberin, …
the loss of heterozygosity of either TSC1 or TSC2, which encode Hamartin or Tuberin, …
[PDF][PDF] A novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE
…, C Bessia, O LeBail, JR Doedens, A Cumano, P Roux… - Molecular cell, 2000 - cell.com
… The activity of presenilin 1 25 rue du Dr Roux 75724 Paris Cedex 15 … precursor and Chambon,
P. (1989). The human estrogen receptor has two protein by a disintegrin metalloprotease. …
P. (1989). The human estrogen receptor has two protein by a disintegrin metalloprotease. …
Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase
Tuberous sclerosis complex (TSC) is a genetic disorder caused by mutations in either of the
two tumor suppressor genes TSC1 or TSC2, which encode hamartin and tuberin, …
two tumor suppressor genes TSC1 or TSC2, which encode hamartin and tuberin, …
Rapamycin differentially inhibits S6Ks and 4E-BP1 to mediate cell-type-specific repression of mRNA translation
The mammalian translational initiation machinery is a tightly controlled system that is
composed of eukaryotic initiation factors, and which controls the recruitment of ribosomes to …
composed of eukaryotic initiation factors, and which controls the recruitment of ribosomes to …
Large-scale 3D printing of ultra-high performance concrete–a new processing route for architects and builders
In the present paper a new additive manufacturing processing route is introduced for ultra-high
performance concrete. Interdisciplinary work involving materials science, computation, …
performance concrete. Interdisciplinary work involving materials science, computation, …
[HTML][HTML] RAS/ERK signaling promotes site-specific ribosomal protein S6 phosphorylation via RSK and stimulates cap-dependent translation
Converging signals from the mammalian target of rapamycin (mTOR) and phosphoinositide
3-kinase (PI3K) pathways are well established to modulate translation initiation. Less is …
3-kinase (PI3K) pathways are well established to modulate translation initiation. Less is …
Extracting time‐domain Green's function estimates from ambient seismic noise
It has been demonstrated experimentally and theoretically that an estimate of the Green's
function between two seismic stations can be obtained from the time‐derivative of the long‐…
function between two seismic stations can be obtained from the time‐derivative of the long‐…