User profiles for P. Plavén-Sigray

Pontus Plavén-Sigray

Researcher, Karolinska Institutet and Copenhagen University Hospital
Verified email at ki.se
Cited by 1055

The readability of scientific texts is decreasing over time

P Plavén-Sigray, GJ Matheson, BC Schiffler… - Elife, 2017 - elifesciences.org
10.7554/eLife.27725.001 Clarity and accuracy of reporting are fundamental to the scientific
process. Readability formulas can estimate how difficult a text is to read. Here, in a corpus …

[HTML][HTML] Positron emission tomography studies of the glial cell marker translocator protein in patients with psychosis: a meta-analysis using individual participant data

P Plavén-Sigray, GJ Matheson, K Collste, AH Ashok… - Biological …, 2018 - Elsevier
… For completeness, we also present frequentist equivalents of the best-fitting model, showing
p values for patient–control differences in standardized V T for each ROI in Supplemental …

Lower levels of the glial cell marker TSPO in drug-naive first-episode psychosis patients as measured using PET and [11C] PBR28

K Collste, P Plavén-Sigray, H Fatouros-Bergman… - Molecular …, 2017 - nature.com
Several lines of evidence are indicative of a role for immune activation in the pathophysiology
of schizophrenia. Nevertheless, studies using positron emission tomography (PET) and …

[HTML][HTML] Effects of age, BMI and sex on the glial cell marker TSPO — a multicentre [11C]PBR28 HRRT PET study

J Tuisku, P Plavén-Sigray, EC Gaiser, L Airas… - European journal of …, 2019 - Springer
Purpose The purpose of this study was to investigate the effects of ageing, sex and body
mass index (BMI) on translocator protein (TSPO) availability in healthy subjects using positron …

Meta-analysis of the glial marker TSPO in psychosis revisited: reconciling inconclusive findings of patient–control differences

P Plavén-Sigray, GJ Matheson… - Biological …, 2021 - biologicalpsychiatryjournal.com
… We found no age-by-group interaction effect on V T in any of the examined regions (all p >
.6… the observed differences is reduced compared with those observed in Plavén-Sigray et al. ( …

[HTML][HTML] Thalamic dopamine D2-receptor availability in schizophrenia: a study on antipsychotic-naive patients with first-episode psychosis and a meta-analysis

P Plavén-Sigray, P Ikonen Victorsson, A Santillo… - Molecular …, 2022 - nature.com
Pharmacological and genetic evidence support a role for an involvement of the dopamine
D2-receptor (D2-R) in the pathophysiology of schizophrenia. Previous molecular imaging …

Cognitive Function and Variability in Antipsychotic Drug–Naive Patients With First-Episode Psychosis: A Systematic Review and Meta-Analysis

M Lee, M Cernvall, J Borg, P Plavén-Sigray… - JAMA …, 2024 - jamanetwork.com
… The study examining cognitive variability in those at CHR-P also included a small group of
patients with FEP who exhibited similar within-group variability as those at CHR-P, but to our …

Prediction of brain age using structural magnetic resonance imaging: A comparison of accuracy and test–retest reliability of publicly available software packages

…, JE Svensson, P PlavénSigray - Human Brain …, 2023 - Wiley Online Library
Brain age prediction algorithms using structural magnetic resonance imaging (MRI) aim to
assess the biological age of the human brain. The difference between a person's …

[HTML][HTML] Serotonin transporter availability increases in patients recovering from a depressive episode

JE Svensson, C Svanborg, P Plavén-Sigray… - Translational …, 2021 - nature.com
… after treatment (p = 0.01), while no change was observed in the median raphe (p = 0.51). No
… were observed in the composite region (p = 0.97) or the median raphe (p = 0.95). Our main …

Brain neuroreceptor density and personality traits: towards dimensional biomarkers for psychiatric disorders

L Farde, P Plavén-Sigray, J Borg… - … Transactions of the …, 2018 - royalsocietypublishing.org
Positron emission tomography has, for 30 years, been used in numerous case-control
studies searching for hypothesized differences in the density of neuroreceptor or transporter …