Curcumin suppresses proliferation and induces apoptosis in human biliary cancer cells through modulation of multiple cell signaling pathways

…, SC Gupta, JH Kim, B Sung, P Pinlaor… - …, 2011 - academic.oup.com
… Since STAT-3 phosphorylation requires JAK-1 activation, we investigated the effect of
curcumin on expression of p-JAK-1 in KKU-M156 cells. As is evident from Figure 4C , curcumin …

Curcumin decreases cholangiocarcinogenesis in hamsters by suppressing inflammation‐mediated molecular events related to multistep carcinogenesis

…, P Pinlaor, BB Aggarwal, S Pinlaor - … journal of cancer, 2011 - Wiley Online Library
p values less than 0.05 were considered statistically significant. … In OV + NDMA group,
expression of phosphorylated (p)-p65 in nuclear extracts was observed in relation to CCA …

Involvement of MMP‐9 in peribiliary fibrosis and cholangiocarcinogenesis via Rac1‐dependent DNA damage in a hamster model

…, P Sithithaworn, P Pinlaor, S Pinlaor - … journal of cancer, 2010 - Wiley Online Library
p values less than 0.05 were considered statistically significant. … a, b, c and d are statistically
different by one-way ANOVA analysis among 4 groups (p < 0.05). The experiment and …

iNOS‐dependent DNA damage via NF‐κB expression in hamsters infected with Opisthorchis viverrini and its suppression by the antihelminthic drug praziquantel

…, N Ma, P Pinlaor, P Sithithaworn… - … journal of cancer, 2006 - Wiley Online Library
… drug praziquantel - Pinlaor - 2006 - … (p<0.01). 8-oxodG level in the liver of OV-infected
hamsters was significantly decreased by praziquantel treatment on days 14 (p< 0.01) and 30 (p<…

Subtype identification of Blastocystis spp. isolated from patients in a major hospital in northeastern Thailand

S Jantermtor, P Pinlaor, K Sawadpanich, S Pinlaor… - Parasitology …, 2013 - Springer
The present study is aimed to identify the prevalence of Blastocystis subtypes isolated from
patients in a major hospital in northeastern Thailand. A total of 562 stool samples were …

[HTML][HTML] Gene discovery for the carcinogenic human liver fluke, Opisthorchis viverrini

T Laha, P Pinlaor, J Mulvenna, B Sripa, M Sripa… - BMC genomics, 2007 - Springer
Background Cholangiocarcinoma (CCA) – cancer of the bile ducts – is associated with chronic
infection with the liver fluke, Opisthorchis viverrini. Despite being the only eukaryote that …

[HTML][HTML] Distribution and abundance of Opisthorchis viverrini metacercariae in cyprinid fish in Northeastern Thailand

…, S Onsurathum, T Boonmars, P Pinlaor… - The Korean journal of …, 2013 - ncbi.nlm.nih.gov
… A P-value less than 0.05 was considered statistically significant. … proctozysron, and P.
orphoides were found to be infected with OV MC. Fish collected from water bodies in Si Sa Ket, …

[HTML][HTML] High prevalence of chronic kidney disease and its related risk factors in rural areas of Northeast Thailand

U Cha'on, P Tippayawat, N Sae-Ung, P Pinlaor… - Scientific Reports, 2022 - nature.com
In Thailand, chronic kidney disease (CKD) screening was reported in 2009 with an overall
prevalence of 17.5% and the highest at 22.2% in the northeastern region. This study aimed to …

Curcumin reduces oxidative and nitrative DNA damage through balancing of oxidant–antioxidant status in hamsters infected with Opisthorchis viverrini

S Pinlaor, P Yongvanit, S Prakobwong… - Molecular nutrition & …, 2009 - Wiley Online Library
Opisthorchis viverrini (OV) infection is endemic in northeastern Thailand. We have previously
reported that OV infection induces oxidative and nitrative DNA damage via chronic …

[PDF][PDF] Oxidative and nitrative stress in Opisthorchis viverrini-infected hamsters: an indirect effect after praziquantel treatment

…, T Boonmars, P Sithithaworn, P Pinlaor… - American Journal of …, 2008 - academia.edu
Praziquantel causes adverse effects after short-term treatment. To examine the mechanism
of these effects, we studied the distribution of Opisthorchis viverrini antigens and the …