… The absolute axial configuration can be indicated by using the stereochemical descriptors P
… The descriptors (R p ) and (S p ) indicate that assigned absolute configuration is referred to …

Since its initial release in 2000, the human reference genome has covered only the
euchromatic fraction of the genome, leaving important heterochromatic regions unfinished. …

We present single-molecule, real-time sequencing data obtained from a DNA polymerase
performing uninterrupted template-directed synthesis using four distinguishable fluorescently …

The DNA sequencing technologies in use today produce either highly accurate short reads
or less-accurate long reads. We report the optimization of circular consensus sequencing (…

… We aligned p-contigs and haplotigs to the parental inbred assemblies to evaluate the accuracy
of haplotype separations. Ideally, each haplotig should be identical to one of the parental …

Background A large outbreak of diarrhea and the hemolytic–uremic syndrome caused by an
unusual serotype of Shiga-toxin–producing Escherichia coli (O104:H4) began in Germany …

The human reference genome assembly plays a central role in nearly all aspects of today's
basic and clinical research. GRCh38 is the first coordinate-changing assembly update since …

Background Although cholera has been present in Latin America since 1991, it had not
been epidemic in Haiti for at least 100 years. Recently, however, there has been a severe …

CDs are cyclic oligosaccharides consisting of α‐d‐glucopyranosyl units linked through 1,4‐linkages,
which are obtained from enzymatic degradation of starch. The coexistence of …

… maps were aligned and merged with RefAligner 32 (P < 1 × 10 −11 ). These initial hybrid
scaffolds were aligned again to the sequence contigs using a less stringent P value (1 × 10 −8 )…