… in Firmicutes (P < 0.001), … (P < 0.001) in BF than in EU children. Also, Enterobacteriaceae
(Shigella and Escherichia) were significantly underrepresented in BF than in EU children (P < …

Children and adolescents with Crohn's disease (CD) present often with a more complicated
disease course compared to adult patients. In addition, the potential impact of CD on growth, …

The incidence of Crohn disease (CD) has been increasing and surgery needs to be
contemplated in a substantial number of cases. The relevant advent of biological treatment has …

Scurvy is a well-known clinical condition caused by vitamin C deficiency. Although considered
a rare disease in high-income countries, it has been recently increasingly reported in …

Tumour necrosis factor (TNF) plays an important role in the pathogenesis of immune-mediated
inflammatory diseases (IMIDs). TNF inhibition results in down-regulation of abnormal and …

Background: The diagnosis of pediatric-onset inflammatory bowel disease (PIBD) can be
challenging in choosing the most informative diagnostic tests and correctly classifying PIBD …

Methods: A group of 27 experts in pediatric IBD participated in an iterative consensus
process including 2 face-to-face meetings, following an open call to ESPGHAN and ECCO …

Previous genome-wide association (GWA) studies typically focus on single-locus analysis,
which may not have the power to detect the majority of genuinely associated loci. Here, we …

… : abdominal pain/discomfort (P< 0.05), abdominal bloating/gassiness (P< 0.05), and family
assessment of life disruption (P< 0.01). No significant difference was found (P= 0.06) in the …

Objectives: Eosinophilic esophagitis (EoE) represents a chronic, immune/antigen-mediated
esophageal disease characterized clinically by symptoms related to esophageal dysfunction …