The ‘pan-genome' denotes the set of all genes present in the genomes of a group of
organisms. Here, we extend the pan-genome concept to higher taxonomic units. Using 573 …

Ketone bodies are produced in the liver, mainly from the oxidation of fatty acids, and are
exported to peripheral tissues for use as an energy source. They are particularly important for …

Immune checkpoint inhibitors (ICI) are being increasingly used to successfully treat several
types of cancer. However, due to their mode of action, these treatments are associated with …

Soil bacteria that also form mutualistic symbioses in plants encounter two major levels of
selection. One occurs during adaptation to and survival in soil, and the other occurs in concert …

Since publication of the first Thermotogales genome, Thermotoga maritima strain MSB8,
single- and multi-gene analyses have disagreed on the phylogenetic position of this order of …

Background & Aims: Anti–liver cytosol type 1 autoantibodies have been reported in
association with anti–liver-kidney microsome type 1 autoantibodies in 30% of patients with …

RNA-seq technologies have provided significant insight into the transcription networks of
mycobacteria. However, such studies provide no definitive information on the translational …

Salmonella enterica serovar Enteritidis is a significant cause of gastrointestinal illness in the
United States; however, current molecular subtyping methods lack resolution for this highly …

Autoimmune hepatitis (AIH) is characterized by an immune‐mediated injury of the hepatic
parenchyma of unknown pathogenesis. Type 2 AIH is identified by the presence of anti‐liver‐…

Whole-genome sequencing (WGS) is a newer alternative for tuberculosis (TB) diagnostics
and is capable of providing rapid drug resistance profiles while performing species …