User profiles for P. Hopkins

Philip Hopkins

Professor of Theoretical Astrophysics, California Institute of Technology
Verified email at caltech.edu
Cited by 52655

Mutations in RYR1 in malignant hyperthermia and central core disease

…, D Carpenter, MA Shaw, J Halsall, P Hopkins - Human …, 2006 - Wiley Online Library
The RYR1 gene encodes the skeletal muscle isoform ryanodine receptor and is fundamental
to the process of excitation–contraction coupling and skeletal muscle calcium homeostasis. …

Molecular biology of atherosclerosis

PN Hopkins - Physiological reviews, 2013 - journals.physiology.org
At least 468 individual genes have been manipulated by molecular methods to study their
effects on the initiation, promotion, and progression of atherosclerosis. Most clinicians and …

A survey of 246 suggested coronary risk factors

PN Hopkins, RR Williams - Atherosclerosis, 1981 - Elsevier
Studies of coronary heart disease (CHD) have led medical investigators to suggest an
association with CHD for at least 246 factors. Though cause and effect relationships have not …

[HTML][HTML] A cosmological framework for the co-evolution of quasars, supermassive black holes, and elliptical galaxies. I. Galaxy mergers and quasar activity

PF Hopkins, L Hernquist, TJ Cox… - The Astrophysical …, 2008 - iopscience.iop.org
We develop a model for the cosmological role of mergers in the evolution of starbursts, quasars,
and spheroidal galaxies. By combining theoretically well-constrained halo and subhalo …

A general theory of turbulent fragmentation

PF Hopkins - Monthly Notices of the Royal Astronomical Society, 2013 - academic.oup.com
… Moreover, in Hopkins (2013, hereafter Paper III) and Hopkins (2012c), we showed how to
calculate other properties of these ‘last-crossings’ such as their correlation functions and …

[HTML][HTML] A phase 3 trial of pirfenidone in patients with idiopathic pulmonary fibrosis

…, MK Glassberg, E Gorina, PM Hopkins… - New England journal …, 2014 - Mass Medical Soc
… (P<0.001). Pirfenidone reduced the decline in the 6-minute walk distance (P=0.04) and improved
progression-free survival (P… scores (P=0.16) or in rates of death from any cause (P=0.10…

[HTML][HTML] A unified, merger-driven model of the origin of starbursts, quasars, the cosmic X-ray background, supermassive black holes, and galaxy spheroids

PF Hopkins, L Hernquist, TJ Cox… - The Astrophysical …, 2006 - iopscience.iop.org
We present an evolutionary model for starbursts, quasars, and spheroidal galaxies in which
mergers between gas-rich galaxies drive nuclear inflows of gas, producing starbursts and …

CANDELS: the cosmic assembly near-infrared deep extragalactic legacy survey

…, NP Hathi, B Haeussler, PF Hopkins… - The Astrophysical …, 2011 - iopscience.iop.org
The Cosmic Assembly Near-infrared Deep Extragalactic Legacy Survey (CANDELS) is designed
to document the first third of galactic evolution, over the approximate redshift (z) range 8…

Molecular basis of human hypertension: role of angiotensinogen

…, PN Hopkins, RR Williams, JM Lalouel, P Corvol - Cell, 1992 - cell.com
Essential hypertension is a common human disease believed to reautt from the interplay of
multiple genetic and environmental determinants. In genetic studies of two large panels of …

CANDELS: the cosmic assembly near-infrared deep extragalactic legacy survey—the Hubble Space Telescope observations, imaging data products, and mosaics

…, B Häussler, J Herrington, PF Hopkins… - The Astrophysical …, 2011 - iopscience.iop.org
This paper describes the Hubble Space Telescope imaging data products and data reduction
procedures for the Cosmic Assembly Near-infrared Deep Extragalactic Legacy Survey (…