OBJECTIVE: Rheumatoid arthritis is associated with increased cardiovascular morbidity and
mortality. We performed a systematic review of the literature and a meta-analysis to look for …

Background A wide variety of scoring systems have been proposed to assess severity of
psoriasis. Given its importance as a health issue both for patients and health care systems, it is …

Multiple sclerosis (MS) is a prevalent inflammatory disease of the central nervous system that
often leads to disability in young adults. Treatment options are limited and often only partly …

Using the ImmunoChip custom genotyping array, we analyzed 14,498 subjects with multiple
sclerosis and 24,091 healthy controls for 161,311 autosomal variants and identified 135 …

… ] and 43.3 kPa [33.3–75.0] respectively (P < 0.01). The median values of prothrombin index
in … To assess the significance of the association with HVPG ≥10 mmHg, the P-values of chi-…

Objective To characterize the accrual of long‐term disability in a cohort of actively treated
multiple sclerosis (MS) patients and to assess whether clinical and magnetic resonance …

… the nominal p-values was determined by comparing the distribution of the most significant p
values … if the nominal association p-value is greater than the 0.05 tail of the minimal p-value …

… new T2 lesions (p value for … p value for the test of trend was 0.032. There was no apparent
interaction of DMT with vitamin D levels (p = 0.56), of HLA-DRB1 status with vitamin D levels (p …

Methods The CORONADO initiative is a French nationwide multicentre study of patients with
diabetes hospitalised for COVID-19 with a 28-day follow-up. The patients were screened …

… = 0.02) (Figure 6 and Supplemental Table 4); IGHV4-39 and IGHV4-4 are marginally
overrepresented in MS B cell clusters (P = 0.06 and P = 0.07, respectively). In contrast, in PB IGHV3-…