Characterized primarily by a low body-mass index, anorexia nervosa is a complex and
serious illness 1 , affecting 0.9–4% of women and 0.3% of men 2 , 3 – 4 , with twin-based …

INTRODUCTION The brain is responsible for cognition, behavior, and much of what makes
us uniquely human. The development of the brain is a highly complex process, and this …

With few exceptions, the marked advances in knowledge about the genetic basis of schizophrenia
have not converged on findings that can be confidently used for precise experimental …

Schizophrenia has a heritability of 60–80% 1 , much of which is attributable to common risk
alleles. Here, in a two-stage genome-wide association study of up to 76,755 individuals with …

Major depressive disorder (MDD) is a common illness accompanied by considerable
morbidity, mortality, costs, and heightened risk of suicide. We conducted a genome-wide …

Schizophrenia is strongly familial yet rarely (if ever) exhibits classical Mendelian inheritance
patterns. The advent of large-scale genotyping and sequencing projects has yielded large …

Genotyping microarrays are an important resource for genetic mapping, population genetics,
and monitoring of the genetic integrity of laboratory stocks. We have developed the third …

Copy number variants (CNVs) have been strongly implicated in the genetic etiology of
schizophrenia (SCZ). However, genome-wide investigation of the contribution of CNV to risk has …

… The PGSs in each target cohort were scaled by standardizing the PGSs of controls and
applying the standardization to cases: P G S c a s e − m e a n ( P G S c o n t r o l ) S D ( P G S c o …

Genome-wide mapping of chromatin interactions at high resolution remains experimentally
and computationally challenging. Here we used a low-input "easy Hi-C" protocol to map the …