User profiles for P. Ginsbach

Philip Ginsbach-Chen

University of Edinburgh, School of Informatics
Verified email at ed.ac.uk
Cited by 783

[HTML][HTML] A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing

…, AS Sertier, AM Patch, N Jäger, P Ginsbach… - Nature …, 2015 - nature.com
As whole-genome sequencing for cancer genome analysis becomes a clinical tool, a full
understanding of the variables affecting sequencing analysis output is required. Here using …

[HTML][HTML] Genomic footprints of activated telomere maintenance mechanisms in cancer

L Sieverling, C Hong, SD Koser, P Ginsbach… - Nature …, 2020 - nature.com
Cancers require telomere maintenance mechanisms for unlimited replicative potential. They
achieve this through TERT activation or alternative telomere lengthening associated with …

[HTML][HTML] TelomereHunter–in silico estimation of telomere content and composition from cancer genomes

L Feuerbach, L Sieverling, KI Deeg, P Ginsbach… - BMC …, 2019 - Springer
Background Establishment of telomere maintenance mechanisms is a universal step in
tumor development to achieve replicative immortality. These processes leave molecular …

M3 semantic API migrations

B Collie, P Ginsbach, J Woodruff, A Rajan… - Proceedings of the 35th …, 2020 - dl.acm.org
… to the fragment vocabulary, and sample fragments according to the probability P(𝑓𝑛 |𝑓𝑛−1)
until the end symbol is sampled. The conditional probability P(𝑓𝑛 |𝑓𝑛−1) is trained using …

Automatic matching of legacy code to heterogeneous APIs: An idiomatic approach

P Ginsbach, T Remmelg, M Steuwer, B Bodin… - Proceedings of the …, 2018 - dl.acm.org
Heterogeneous accelerators often disappoint. They provide the prospect of great performance,
but only deliver it when using vendor specific optimized libraries or domain specific …

Genetic imbalance in patients with cervical artery dissection

…, B Chen, M Krawczak, R Pjontek, P Ginsbach… - Current …, 2017 - ingentaconnect.com
… subjects (p=0.003; odds ratio (OR) =2.5; 95% confidence interval (95% CI) =1.4-4.5) and
more common in patients with a familial history of CeAD than in those with sporadic CeAD (p=…

[HTML][HTML] Tick-borne encephalitis virus (TBEV) prevalence in field-collected ticks (Ixodes ricinus) and phylogenetic, structural and virulence analysis in a TBE high-risk …

D Ott, K Ulrich, P Ginsbach, R Öhme… - Parasites & …, 2020 - Springer
Background Tick-borne encephalitis (TBE) is the most common viral CNS infection with
incidences much higher than all other virus infections together in many risk areas of central and …

Genetic imbalance is associated with functional outcome after ischemic stroke

D Pfeiffer, B Chen, K Schlicht, P Ginsbach, S Abboud… - Stroke, 2019 - Am Heart Assoc
… The additional models focusing on large imbalances only (CADISP P<0.001 and SiGN/GISCOME
P=0.017) or using propensity scores (CADISP P=0.002 and SiGN/GISCOME P=0.012) …

CAnDL: a domain specific language for compiler analysis

P Ginsbach, L Crawford, MFP O'boyle - Proceedings of the 27th …, 2018 - dl.acm.org
Optimizing compilers require sophisticated program analysis and transformations to exploit
modern hardware. Implementing the appropriate analysis for a compiler optimization is a …

Type-directed program synthesis and constraint generation for library portability

B Collie, P Ginsbach… - 2019 28th International …, 2019 - ieeexplore.ieee.org
… The first row for each application gives the total number of potential matches we identified
by hand-examination (positives, P), with the number of these corresponding to inlined library …