Leveraging genome-wide data to investigate differences between opioid use vs. opioid dependence in 41,176 individuals from the Psychiatric Genomics Consortium

, … Genomics Consortium Substance Use Disorders … - Molecular …, 2020 - nature.com
To provide insights into the biology of opioid dependence (OD) and opioid use (ie, exposure,
OE), we completed a genome-wide analysis comparing 4503 OD cases, 4173 opioid-…

International network of cancer genome projects

, … )(India) Majumder (Leader) Partha P. 67 Sarin Rajiv 52 … - Nature, 2010 - nature.com
… Cancer Genome Consortium (ICGC) was launched to coordinate large-scale cancer genome
… Systematic studies of more than 25,000 cancer genomes at the genomic, epigenomic and …

Evidence of causal effect of major depression on alcohol dependence: findings from the psychiatric genomics consortium

R Polimanti, RE Peterson, JS Ong… - Psychological …, 2019 - cambridge.org
… generated by large datasets from the Psychiatric Genomics Consortium (PGC) and the
UK … To correct for multiple testing, we adopted a Bonferroni corrected P-value threshold of …

The TB Structural Genomics Consortium: a decade of progress

N Chim, JE Habel, JM Johnston, I Krieger, L Miallau… - Tuberculosis, 2011 - Elsevier
… The TB Structural Genomics Consortium is a worldwide … Congruent to the overall vision,
Consortium members have … This review aims to share the latest Consortium developments …

Genome-wide analyses of smoking behaviors in schizophrenia: findings from the Psychiatric Genomics Consortium

, … Group of the Psychiatric Genomics Consortium - Journal of psychiatric …, 2021 - Elsevier
… , we computed several scores based on varying P-value threshold signifying the proportion
of SNPs with smaller P-values in the training set; P-value thresholds (Pt) ranged between …

[HTML][HTML] The genomic standards consortium

…, G Cochrane, JR Cole, P Dawyndt… - PLoS …, 2011 - journals.plos.org
… range of current activities, and make a call for the scientific community to join forces to improve
the quality and quantity of contextual information about our public collections of genomes, …

Psychiatric genomics: an update and an agenda

…, Psychiatric Genomics Consortium - American Journal of …, 2018 - Am Psychiatric Assoc
… The Psychiatric Genomics Consortium (PGC) is the largest consortium in the history of psychiatry.
… These loci are highly significant with p values ranging from 1.7×10 −13 to 3.8×10 −32 . …

[HTML][HTML] … causal relationship of C-reactive protein with 32 complex somatic and psychiatric outcomes: a large-scale cross-consortium Mendelian randomization study

…, Treat OA consortium, DIAGRAM Consortium… - PLoS …, 2016 - journals.plos.org
genome-wide association study (GWAS) to date (GRS GWAS ). To optimize power, we used
summary statistics from GWAS consortia and … An observed p-value equal to or less than 0.05 …

[HTML][HTML] … -wide association for major depression through age at onset stratification: major depressive disorder working group of the psychiatric genomics consortium

…, CARDIoGRAM Consortium, GERAD1 Consortium - Biological …, 2017 - Elsevier
… a p value threshold (P T ) to restrict to the most significant SNPs in their original genome-wide
association analysis (P T … due to overlapping control subjects with the respective consortia. …

Does childhood trauma moderate polygenic risk for depression? A meta-analysis of 5765 subjects from the psychiatric genomics consortium

…, J Marchini, H Mbarek, P McGrath, P McGuffin… - Biological …, 2018 - Elsevier
… Data were combined from 3024 MDD cases and 2741 control subjects from nine cohorts
contributing to the MDD Working Group of the Psychiatric Genomics Consortium. MDD-PRS …