User profiles for P. Deloukas

Panos Deloukas

Professor of Cardiovascular Genomics, Queen Mary University of London
Verified email at qmul.ac.uk
Cited by 283174

A gene map of the human genome

…, DR Cox, MR James, D Bentley, P Deloukas… - Science, 1996 - science.org
The human genome is thought to harbor 50,000 to 100,000 genes, of which about half have
been sampled to date in the form of expressed sequence tags. An international consortium …

Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption

…, JJ Hottenga, I Prokopenko, A Tönjes, P Deloukas… - Molecular …, 2015 - nature.com
Coffee, a major dietary source of caffeine, is among the most widely consumed beverages in
the world and has received considerable attention regarding health risks and benefits. We …

A meta-analysis of genome-wide association studies identifies novel variants associated with osteoarthritis of the hip

…, K Chapman, AG Day-Williams, P Deloukas… - Annals of the …, 2014 - ard.bmj.com
Objectives Osteoarthritis (OA) is the most common form of arthritis with a clear genetic component.
To identify novel loci associated with hip OA we performed a meta-analysis of genome…

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

…, H Gurling, A McQuillin, R Gwilliam, P Deloukas… - Nature …, 2009 - nature.com
We undertook a two-stage genome-wide association study (GWAS) of Alzheimer's disease (AD)
involving over 16,000 individuals, the most powerful AD GWAS to date. In stage 1 (3,941 …

The international HapMap project

…, MMY Waye, LR Cardon, MJ Daly, P Deloukas… - 2003 - deepblue.lib.umich.edu
The goal of the International HapMap Project is to determine the common patterns of DNA
sequence variation in the human genome and to make this information freely available in the …

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

…, H Gurling, A McQuillin, R Gwilliam, P Deloukas… - Nature …, 2011 - nature.com
We sought to identify new susceptibility loci for Alzheimer's disease through a staged
association study (GERAD+) and by testing suggestive loci reported by the Alzheimer's Disease …

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

…, S Bumpstead, R Gwilliam, M Tremelling, P Deloukas… - Nature …, 2008 - nature.com
… suspected but not previously conclusively established in CD) did not reach this conservative
threshold, but so convincingly satisfy proposed thresholds for genome-wide significance (P

[HTML][HTML] Genomewide association analysis of coronary artery disease

…, I Braenne, C Gieger, P Deloukas… - … England Journal of …, 2007 - Mass Medical Soc
Background Modern genotyping platforms permit a systematic search for inherited components
of complex diseases. We performed a joint analysis of two genomewide association …

Common variants near MC4R are associated with fat mass, weight and risk of obesity

…, P Vollenweider, G Waeber, V Mooser, P Deloukas… - Nature …, 2008 - nature.com
To identify common variants influencing body mass index (BMI), we analyzed genome-wide
association data from 16,876 individuals of European descent. After previously reported …

Genome-wide association study identifies eight loci associated with blood pressure

…, S Hercberg, GM Lathrop, D Zelenika, P Deloukas… - Nature …, 2009 - nature.com
Elevated blood pressure is a common, heritable cause of cardiovascular disease worldwide.
To date, identification of common genetic variants influencing blood pressure has proven …