Background SAMtools and BCFtools are widely used programs for processing and analysing
high-throughput sequencing data. They include tools for file format conversion and …

The variant call format (VCF) is a generic format for storing DNA polymorphism data such as
SNPs, insertions, deletions and structural variants, together with rich annotations. VCF is …

We report genome sequences of 17 inbred strains of laboratory mice and identify almost ten
times more variants than previously known. We use these genomes to explore the …

… All differences were significant (binomial P ≤ 0.003 for each comparison of Eagle2 with
SHAPEIT2, P ≤ 0.02 for each comparison with Eagle1, and P = 10 −21 for each comparison …

… P values from analysis of the undiagnosed subset for discordant and novel genes; P values
for consensus genes come from the full cohort analysis. The number of genes in each P-…

The extent to which low‐frequency (minor allele frequency (MAF) between 1–5%) and rare (MAF
≤ 1%) variants contribute to complex traits and disease in the general population is …

… This was defined as the number of control variant sets (n) that showed a higher overlap with
the target annotation than the eQTL lead variants (P = n / 100). The empirical P values were …

INTRODUCTION Large-scale human genome-sequencing studies to date have been limited
to large, metropolitan populations or to small numbers of genomes from each group. Much …

The European Integrated Data Archive (EIDA) is the infrastructure that provides access to
the seismic‐waveform archives collected by European agencies. This distributed system is …

Background The mouse inbred line C57BL/6J is widely used in mouse genetics and its
genome has been incorporated into many genetic reference populations. More recently large …