The cancer genome
MR Stratton, PJ Campbell, PA Futreal - Nature, 2009 - nature.com
All cancers arise as a result of changes that have occurred in the DNA sequence of the
genomes of cancer cells. Over the past quarter of a century much has been learnt about these …
genomes of cancer cells. Over the past quarter of a century much has been learnt about these …
Speech and language therapy for aphasia following stroke
Background Aphasia is an acquired language impairment following brain damage that affects
some or all language modalities: expression and understanding of speech, reading, and …
some or all language modalities: expression and understanding of speech, reading, and …
Somatic mutation in cancer and normal cells
I Martincorena, PJ Campbell - Science, 2015 - science.org
Spontaneously occurring mutations accumulate in somatic cells throughout a person’s lifetime.
The majority of these mutations do not have a noticeable effect, but some can alter key …
The majority of these mutations do not have a noticeable effect, but some can alter key …
[HTML][HTML] Osteoprotegerin: a novel secreted protein involved in the regulation of bone density
…, P Campbell, S Sander, G Van, J Tarpley, P Derby… - cell, 1997 - cell.com
A novel secreted glycoprotein that regulates bone resorption has been identified. The protein,
termed Osteoprotegerin (OPG), is a novel member of the TNF receptor superfamily. In vivo, …
termed Osteoprotegerin (OPG), is a novel member of the TNF receptor superfamily. In vivo, …
[HTML][HTML] Massive genomic rearrangement acquired in a single catastrophic event during cancer development
…, AM Flanagan, MR Stratton, PA Futreal, PJ Campbell - cell, 2011 - cell.com
Cancer is driven by somatically acquired point mutations and chromosomal rearrangements,
conventionally thought to accumulate gradually over time. Using next-generation …
conventionally thought to accumulate gradually over time. Using next-generation …
Patterns of somatic mutation in human cancer genomes
…, A DeFazio, MF Greaves, AR Green, P Campbell… - Nature, 2007 - nature.com
Cancers arise owing to mutations in a subset of genes that confer growth advantage. The
availability of the human genome sequence led us to propose that systematic resequencing of …
availability of the human genome sequence led us to propose that systematic resequencing of …
Signatures of mutational processes in human cancer
All cancers are caused by somatic mutations; however, understanding of the biological
processes generating these mutations is limited. The catalogue of somatic mutations from a …
processes generating these mutations is limited. The catalogue of somatic mutations from a …
[HTML][HTML] Genomic classification and prognosis in acute myeloid leukemia
Background Recent studies have provided a detailed census of genes that are mutated in
acute myeloid leukemia (AML). Our next challenge is to understand how this genetic diversity …
acute myeloid leukemia (AML). Our next challenge is to understand how this genetic diversity …
Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages.
VA Fadok, DR Voelker, PA Campbell… - … (Baltimore, Md.: 1950 …, 1992 - journals.aai.org
… Colorado HSC Cancer Center for assistance in growing bulk cultures of CTLL-2 cells, William
Townend of the Cytometry Lab at NJC for assistance with flow cytometry, Sheryl Campbell …
Townend of the Cytometry Lab at NJC for assistance with flow cytometry, Sheryl Campbell …
[BOOK][B] The Study
P Campbell - 1982 - books.google.com
She watches her own eyes, thinking about her character. Thinks on the actions that shall
signify something about her, none of her past actions having suggested anything of note, other …
signify something about her, none of her past actions having suggested anything of note, other …