User profiles for P. Brodskiy

Pavel A. Brodskiy

Machine Learning Engineer, Iterative Scopes
Verified email at iterativescopes.com
Cited by 372

Calcium as a signal integrator in developing epithelial tissues

PA Brodskiy, JJ Zartman - Physical biology, 2018 - iopscience.iop.org
P ij represents the relative permeability of cells i and j, and is 0 when cells are not in contact.
(C) Cartoon representation of Hopf-bifurcation in the parameter domain (p) and in the time …

[PDF][PDF] Decoding calcium signaling dynamics during Drosophila wing disc development

PA Brodskiy, Q Wu, DK Soundarrajan, FJ Huizar… - Biophysical journal, 2019 - cell.com
… For (F and G), p < 0.001 for ordinal logistic regression model … P compartment such that the
AP compartment boundary was approximated with a vertical line fitted to points along the A/P

[HTML][HTML] Multi-scale computational study of the mechanical regulation of cell mitotic rounding in epithelia

A Nematbakhsh, W Sun, PA Brodskiy… - PLoS computational …, 2017 - journals.plos.org
… result in p = 0.72 for cell area ratio and p = 0.76 for normalized roundness of mitotic cells. …
described in Fig 7C–7F after stepwise model regression (p-value cutoff of 0.01). (C) Proposed …

Patterning of wound-induced intercellular Ca2+ flashes in a developing epithelium

C Narciso, Q Wu, P Brodskiy, G Garston… - Physical …, 2015 - iopscience.iop.org
… In the rest of the domain we impose a spatially uniform initial condition at t = 0, with P and
h taking the values zero and one respectively. C takes its steady-state value according to …

Characterization and performance relationships for a commercial thin film composite membrane in forward osmosis desalination and pressure retarded osmosis

…, SS Manickam, KK Reimund, P Brodskiy… - Industrial & …, 2015 - ACS Publications
This paper presents performance data for an early generation thin film composite membrane
from Oasys Water. These tests sought to measure the membrane’s basic chemical and …

[HTML][HTML] Capabilities and limitations of tissue size control through passive mechanical forces

J Kursawe, PA Brodskiy, JJ Zartman… - PLoS computational …, 2015 - journals.plos.org
… In order to simulate the subsections of the P compartment we consider a spatial domain
comprising two adjacent cell populations, the cells in the P compartment and parts of the …

Benefit from upfront FOLFOXIRI and bevacizumab in BRAFV600E-mutated metastatic colorectal cancer patients: does primary tumour location matter?

…, F Corti, G Mauri, M Fassan, G Masi, P Brodskiy… - British Journal of …, 2022 - nature.com
… was reported in terms of both PFS (p = 0.010) and OS (p = 0.003), with a beneficial effect of
… compared to oxaliplatin-based doublets±bevacizumab (p = 0.097 and 0.16 for PFS and OS, …

[HTML][HTML] Genomic and molecular profiling of human papillomavirus associated head and neck squamous cell carcinoma treated with immune checkpoint blockade …

H Shaikh, JE McGrath, B Hughes, J Xiu, P Brodskiy… - Cancers, 2021 - mdpi.com
… 3.3 months, HR 0.632, p = 0.016), suggesting that p16 may be used as a prognostic
biomarker in non-OP HNSCC, and further … Significance was determined as p values <0.05. …

High throughput characterization of adult stem cells engineered for delivery of therapeutic factors for neuroprotective strategies

AD Sharma, PA Brodskiy, EM Petersen… - JoVE (Journal of …, 2015 - jove.com
Mesenchymal stem cells (MSCs) derived from bone marrow are a powerful cellular resource
and have been used in numerous studies as potential candidates to develop strategies for …

[HTML][HTML] MAPPER: An Open-Source, High-Dimensional Image Analysis Pipeline Unmasks Differential Regulation of Drosophila Wing Features

N Kumar, FJ Huizar, PA Brodskiy, M Nahmad… - Frontiers in …, 2022 - frontiersin.org
… The slope parameters of each fit was not statistically different from a value of 1.00 (p =
0.287 for PD axis and p = 0.055 for AP axis). Inset: Raw wing image with a corresponding …