Archaeal and eukaryotic homologs of Hfq: A structural and evolutionary perspective on Sm function

C Mura, PS Randolph, J Patterson, AE Cozen - RNA biology, 2013 - Taylor & Francis
Hfq and other Sm proteins are central in RNA metabolism, forming an evolutionarily
conserved family that plays key roles in RNA processing in organisms ranging from archaea to …

Out-of-register parallel β-sheets and antiparallel β-sheets coexist in 150-kDa oligomers formed by amyloid-β (1–42)

Y Gao, C Guo, JO Watzlawik, PS Randolph… - Journal of molecular …, 2020 - Elsevier
We present solid-state NMR measurements of β-strand secondary structure and inter-strand
organization within a 150-kDa oligomeric aggregate of the 42-residue variant of the …

[HTML][HTML] Characterizing the resolution and throughput of the Apollo direct electron detector

R Peng, X Fu, JH Mendez, PS Randolph… - Journal of Structural …, 2023 - Elsevier
Advances in electron detection have been essential to the success of high-resolution cryo-EM
structure determination. A new generation of direct electron detector called the Apollo, has …

Geological and taphonomic context for the new hominin species Homo naledi from the Dinaledi Chamber, South Africa

…, JD Kramers, J Hawks, PS Randolph-Quinney… - Elife, 2015 - elifesciences.org
10.7554/eLife.09561.001 We describe the physical context of the Dinaledi Chamber within
the Rising Star cave, South Africa, which contains the fossils of Homo naledi. Approximately …

[HTML][HTML] Earliest hominin cancer: 1.7-million-year-old osteosarcoma from Swartkrans Cave, South Africa

EJ Odes, PS Randolph-Quinney, M Steyn… - South African Journal …, 2016 - scielo.org.za
… An invasive spinal lesion has been attributed by Randolph-Quinney and colleagues to benign
osteoid … EJO and PS.RQ wrote the original draft of the manuscript, incorporating additional …

[HTML][HTML] Crystal structure and RNA-binding properties of an Hfq homolog from the deep-branching Aquificae: conservation of the lateral RNA-binding mode

KA Stanek, J Patterson-West, PS Randolph… - … Section D: Structural …, 2017 - scripts.iucr.org
The host factor Hfq, as the bacterial branch of the Sm family, is an RNA-binding protein
involved in the post-transcriptional regulation of mRNA expression and turnover. Hfq facilitates …

[HTML][HTML] Osteogenic tumour in Australopithecus sediba: Earliest hominin evidence for neoplastic disease

PS Randolph-Quinney, SA Williams, M Steyn… - South African Journal …, 2016 - scielo.org.za
We describe the earliest evidence for neoplastic disease in the hominin lineage. This is
reported from the type specimen of the extinct hominin Australopithecus sediba from Malapa, …

[HTML][HTML] Evidence of fatal skeletal injuries on Malapa Hominins 1 and 2

…, S Kuo, DE Raymond, PS Randolph-Quinney… - Scientific Reports, 2015 - nature.com
Malapa is one of the richest early hominin sites in Africa and the discovery site of the hominin
species, Australopithecus sediba. The holotype and paratype (Malapa Hominin 1 and 2, or …

[HTML][HTML] Possible bite-induced abscess and osteomyelitis in Lufengosaurus (Dinosauria: sauropodomorph) from the Lower Jurassic of the Yimen Basin, China

L Xing, BM Rothschild, PS Randolph-Quinney… - Scientific reports, 2018 - nature.com
We report an osseous abnormality on a specimen of the sauropod dinosaur Lufengosaurus
huenei from the Fengjiahe Formation in Yuxi Basin, China. A gross pathological defect …

Comment on “Deliberate body disposal by hominins in the Dinaledi Chamber, Cradle of Humankind, South Africa?”[J. Hum. Evol. 96 (2016) 145–148]

…, LR Berger, J Hawks, PS Randolph-Quinney… - Journal of Human …, 2016 - Elsevier
In responding to Val (2016), we welcome the opportunity to further clarify our interpretations
of the taphonomic and geological context of Homo naledi in the Dinaledi Chamber of the …