Objective HLA alleles affect susceptibility to more than 100 diseases, but the mechanisms
that account for these genotype–disease associations are largely unknown. HLA alleles …

Objectives Diverse evidence including clinical, genetic and microbiome studies support a
major role of the gut microbiome in the common immune-mediated arthropathy, ankylosing …

Wine is a complex beverage, comprising hundreds of metabolites produced through the
action of yeasts and bacteria in fermenting grape must. Commercially, there is now a growing …

Background Oenococcus oeni is a lactic acid bacterium that is specialised for growth in the
ecological niche of wine, where it is noted for its ability to perform the secondary, malolactic …

… Peter R Sternes , Peter R Sternes … Tianjiao Wang, Peter R Sternes, Xue-Kun Guo, Huiying
Zhao, Congmin Xu, Huji Xu, Autoimmune diseases exhibit shared alterations in the gut …

Members of the genus Hanseniaspora represent a significant proportion of the normal flora
of grape berries and play a significant role in wine fermentation. Here, we present genome …

Sustained expression of transgenes in specified developmental patterns is commonly needed
in plant biotechnology, but obstructed by transgene silencing. Here, we present a set of …

Background Multiple studies have confirmed dysbiosis in ankylosing spondylitis (AS) and
inflammatory bowel disease (IBD); however, due to methodological differences across studies, …

Birdshot retinochoroidopathy occurs exclusively in individuals who are HLA-A29 positive.
The mechanism to account for this association is unknown. The gut microbiome has been …

We report the first whole transcriptome RNAseq analysis of the wine-associated lactic acid
bacterium Oenococcus oeni using a combination of reference-based mapping and de novo …