Localization and characterization of 35S-t-butylbicyclophosphorothionate binding in rat brain: an autoradiographic study

PP Edgar, RD Schwartz - Journal of Neuroscience, 1990 - Soc Neuroscience
35S-t-butylbicyclophosphorothionate (TBPS) binding to slide-mounted rat brain sections
was characterized for subsequent autoradiographic analysis. Cortical brain mash slices, …

Functionally relevant gamma-aminobutyric acidA receptors: equivalence between receptor affinity (Kd) and potency (EC50)?

PP Edgar, RD Schwartz - Molecular pharmacology, 1992 - ASPET
Many neurotransmitter receptors bind agonists with high affinity (Kd in the nanomolar range),
whereas micromolar concentrations of the same agonists are required to elicit a functional …

cAMP analogs inhibit gamma-aminobutyric acid-gated chloride flux and activate protein kinase A in brain synaptoneurosomes.

RD Schwartz, G Heuschneider, PP Edgar… - Molecular pharmacology, 1991 - ASPET
The effects of permeant cAMP analogs were studied on the function of the gamma-aminobutyric
acidA (GABAA) receptor and on the activation of protein kinase A in brain …

Regulatory strategy: A blueprint for drug development

LL Miller, PP Edgar, V Lackey… - Drug information …, 1994 - journals.sagepub.com
An efficient drug development process, and rapid review and approval are the goals of
every pharmaceutical sponsor, but numerous factors make this goal difficult and sometimes …

JD Edgar and the Liberal Party: 1867–96

RM Stamp - Canadian Historical Review, 1964 - utpjournals.press
… editor-in-ehieœ that made Edgar a Liberal. Brown introduced Edgar into politics at the time
o• the 1867 Upper Canada Reform convent/on. Although young Edgar had little to say in the …

Indirect measurement of (or ) using pairs from bosons produced in collisions at a center-of-momentum energy of 1.96 TeV

…, M D'Onofrio, M Dorigo, A Driutti, K Ebina, R Edgar… - Physical Review D, 2014 - APS
Drell-Yan lepton pairs are produced in the process pp→ μ+ μ−+ X through an intermediate γ*/Z
boson. The forward-backward asymmetry in the polar-angle distribution of the μ− as a …

Mass and lifetime measurements of bottom and charm baryons in collisions at

…, M D'Onofrio, M Dorigo, A Driutti, K Ebina, R Edgar… - Physical Review D, 2014 - APS
We report on mass and lifetime measurements of several ground state charmed and bottom
baryons, using a data sample corresponding to 9.6 fb− 1 from pp collisions at s= 1.96 TeV …

Measurement of using pairs from bosons produced in collisions at a center-of-momentum energy of 1.96 TeV

…, M D'Onofrio, M Dorigo, A Driutti, K Ebina, R Edgar… - Physical review D, 2016 - APS
At the Fermilab Tevatron proton-antiproton (pp) collider, Drell-Yan lepton pairs are
produced in the process pp→ e+ e−+ X through an intermediate γ*/Z boson. The forward-backward …

Search for Pair Production of Strongly Interacting Particles Decaying to Pairs of Jets in Collisions at

…, S Donati, M Dorigo, A Driutti, K Ebina, R Edgar… - Physical Review Letters, 2013 - APS
We present a search for the pair production of a narrow nonstandard-model strongly
interacting particle that decays to a pair of quarks or gluons, leading to a final state with four …

Measurement of central exclusive production in collisions at and 1.96 TeV at CDF

…, M D'Onofrio, M Dorigo, A Driutti, K Ebina, R Edgar… - Physical Review D, 2015 - APS
We measure exclusive π+ π− production in proton-antiproton collisions at center-of-mass
energies s= 0.9 and 1.96 TeV in the Collider Detector at Fermilab. We select events with two …