… Ding, Shengli; Lund, Pauline K … Lund, PhD, Department of Cell and Molecular
Physiology University of North Carolina at Chapel Hill, 111 Mason Farm Road, CB# 7545 …

… A single treatment with 3–5% DSS does not lead to significant fibrosis at the end of DSS
or during recovery (PK Lund and KL Williams, unpublished observations). We have begun to …

The National Institutes of Health (NIH) is committed to attracting, developing, and supporting
the best scientists from all groups as an integral part of excellence in training. Biomedical …

Background Obesity induced by high fat (HF) diet is associated with inflammation which
contributes to development of insulin resistance. Most prior studies have focused on adipose …

The somatomedins or insulin-like growth factors (IGFs) are synthesized in many organs and
tissues, but the specific cells that synthesize them in vivo have not been defined. By in situ …

Several lines of evidence indicate that multiple human fetal tissues synthesize
somatomedins/insulin-like growth factors (Sm/IGFs). To investigate the synthesis of Sm/IGFs in vivo, …

Although glucagonlike immunoreactants (GLIs) are present in the central nervous system of
several mammalian species, their structural relationship with pancreatic proglucagon is not …

We have constructed and cloned in bacteria recombinant plasmids containing DNA
complementary to the mRNA encoding a pancreatic preproglucagon (Mr 14,500), a product of cell-…

Intestinal fibrosis is an incurable complication of Crohn's disease involving increased
numbers of collagen-producing myofibroblasts. Tumor necrosis factor (TNF) α has defined …

Somatomedin-C or insulin-like growth factor I (Sm-C/IGF-I) and insulin-like growth factor II (IGF-II)
have been implicated in the regulation of fetal growth and development. In the present …