[HTML][HTML] Comprehensive profiling of transcriptional networks specific for lactogenic differentiation of HC11 mammary epithelial stem-like cells

TR Sornapudi, R Nayak, PK Guthikonda… - Scientific Reports, 2018 - nature.com
The development of mammary gland as a lactogenic tissue is a highly coordinated multistep
process. The epithelial cells of lactiferous tubules undergo profound changes during the …

[HTML][HTML] Biased visibility in Hi-C datasets marks dynamically regulated condensed and decondensed chromatin states genome-wide

KR Chandradoss, PK Guthikonda, S Kethavath… - BMC genomics, 2020 - Springer
Background Proximity ligation based techniques, like Hi-C, involve restriction digestion followed
by ligation of formaldehyde cross-linked chromatin. Distinct chromatin states can impact …

Polymorphic dynamics of ribosomal proteins gene expression during somatic cell reprogramming and their differentiation in to specialized cells-types

PK Guthikonda, SP Bharathan, J Rayabaram… - bioRxiv, 2017 - biorxiv.org
Reprogramming of somatic cells into Induced pluripotent stem cells (iPSCs) by defined factors
has been well established. iPSCs were shown to be very similar to Embryonic Stem Cells (…

Spatiotemporal Dynamics of 3D Genome Architecture and Gene Expression during Lactogenic Differentiation of Murine Mammary Epithelial Cells

TR Sornapudi, PK Guthikonda… - Canadian Journal …, 2017 - search.proquest.com
Orchestration of differential gene expression program during cellular development and
differentiation is tightly coordinated in each and every cell type. Cell-type specific gene …

[HTML][HTML] RNA sequencing of murine mammary epithelial stem-like cells (HC11) undergoing lactogenic differentiation and its comparison with embryonic stem cells

TR Sornapudi, R Nayak, PK Guthikonda… - BMC Research …, 2018 - Springer
Objectives Understanding of transcriptional networks specifying HC11 murine mammary
epithelial stem cell-like cells (MEC) in comparison with embryonic stem cells (ESCs) and their …

Syntheses and SAR studies of 4-(heteroarylpiperdin-1-yl-methyl)-pyrrolidin-1-yl-acetic acid antagonists of the human CCR5 chemokine receptor

…, KL Donnelly, SK Shah, RN Guthikonda… - Bioorganic & Medicinal …, 2004 - Elsevier
… This result would prove important for PK reasons as discussed … PK properties. Shown
above are two additional compounds, 53 and 54, that were subsequently evaluated for their PK

Natalizumab-Associated primary central nervous system lymphoma

…, RH Dossani, K Sharma, A Nanda, B Guthikonda - World neurosurgery, 2018 - Elsevier
… The resulting citations were screened in detail for further eligibility in their entirety by 2 authors
independently (PK and KS). Screening was performed by reviewing article titles, abstracts…

Acoustic shock waves emitted from two interacting laser generated plasmas in air

M Elle, N Guthikonda, SS Shiva… - The Journal of the …, 2023 - pubs.aip.org
… The ASW peak sound pressures (Pk) from the interaction zone with respect to the plasma …
At 2 mm separation, the Pk is 5.5 kPa, whereas at 15 mm, the Pk is 8 kPa, confirming a rise …

Effect of laser energy on underwater acoustic shockwave emissions from optical breakdown

Y Janapati, M Elle, N Guthikonda, PK Paturi - ICOL-2019: Proceedings of …, 2021 - Springer
This study is aimed to understand the characteristics of underwater acoustic emissions by ~10
ns laser pulses in the temporal and spectral domain at various incident laser energies. …

[HTML][HTML] Deficient synthesis of glutathione underlies oxidative stress in aging and can be corrected by dietary cysteine and glycine supplementation

RV Sekhar, SG Patel, AP Guthikonda, M Reid… - The American journal of …, 2011 - Elsevier
Background: Aging is associated with oxidative stress, but underlying mechanisms remain
poorly understood. Objective: We tested whether glutathione deficiency occurs because of …