Fitness landscapes 1 , 2 depict how genotypes manifest at the phenotypic level and form the
basis of our understanding of many areas of biology 2 , 3 , 4 , 5 , 6 , 7 , yet their properties …

The aim of this study was to investigate the possible protective role of antioxidant treatment
with syringic acid (SA) on l-arginine–induced acute pancreatitis (AP) using biochemical and …

… NACHT domain) in the dataset using Clustal–Omega, (ii) constructed a phylogeny using a
… our phylogeny on an alignment calculated with Clustal–Omega v. 1.2, reduced to conserved …

Objective: Many cancer patients treated with radiotherapy suffer severe side effects during
and after their treatment. The aim of this study was to investigate the effects of irradiation and …

Nowadays, deep learning is a technique that takes place in many computer vision related
applications and studies. While it is put in the practice mostly on content based image retrieval, …

Despite major progress in defining the genetic basis of Mendelian disorders, the molecular
etiology of many cases remains unknown. Patients with these undiagnosed disorders often …

Extreme disease phenotypes can provide key insights into the pathophysiology of common
conditions, but studying such cases is challenging due to their rarity and the limited statistical …

Whether or not evolutionary change is inherently irreversible remains a controversial topic.
Some examples of evolutionary irreversibility are known; however, this question has not been …

Proteases play important roles in many biologic processes and are key mediators of cancer,
inflammation, and thrombosis. However, comprehensive and quantitative techniques to …

The influence of genetic background on driver mutations is well established; however, the
mechanisms by which the background interacts with Mendelian loci remain unclear. We …