User profiles for O. Griffith
Obi L. GriffithAssociate Professor, Washington University School of Medicine Verified email at wustl.edu Cited by 22808 |
Nitric oxide synthases: properties and catalytic mechanism
OW Griffith, DJ Stuehr - Annual review of physiology, 1995 - annualreviews.org
… That consideration led Narayanan & Griffith to design and synthesize arginine/citrulline
analogues having side chains with func tionalities expected to act as heme-binding ligands (29, …
analogues having side chains with func tionalities expected to act as heme-binding ligands (29, …
Biologic and pharmacologic regulation of mammalian glutathione synthesis
OW Griffith - Free Radical Biology and Medicine, 1999 - Elsevier
… , the cytotoxic Fenton reaction product, and with N 2 O 3 and peroxynitrite, cytotoxic products
formed by the reaction of nitric oxide (NO) with O 2 and superoxide, respectively [5], [6], [7]. …
formed by the reaction of nitric oxide (NO) with O 2 and superoxide, respectively [5], [6], [7]. …
Bacterial phosphatidylinositol-specific phospholipase C: structure, function, and interaction with lipids
OH Griffith, M Ryan - Biochimica et Biophysica Acta (BBA)-Molecular and …, 1999 - Elsevier
The bacterial phosphatidylinositol-specific phospholipase C (PI-PLC) is a small, water-soluble
enzyme that cleaves the natural membrane lipids PI, lyso-PI, and glycosyl-PI. The crystal …
enzyme that cleaves the natural membrane lipids PI, lyso-PI, and glycosyl-PI. The crystal …
Evidence for boundary lipid in membranes
PC Jost, OH Griffith, RA Capaldi… - Proceedings of the …, 1973 - National Acad Sciences
Cytochrome oxidase (EC 1.9.3.1) isolated from beef-heart mitochondria with an appropriate
phospholipid content forms vesicular structures. Lipid-protein interactions in this model …
phospholipid content forms vesicular structures. Lipid-protein interactions in this model …
Shape of the hydrophobic barrier of phospholipid bilayers (evidence for water penetration in biological membranes)
OH Griffith, PJ Dehlinger, SP Van - The Journal of membrane biology, 1974 - Springer
Previous work has shown that there is a small solvent effect on the electron spin resonance
spectra of nitroxide spin labels. The aim of this paper is to develop a semiquantitative …
spectra of nitroxide spin labels. The aim of this paper is to develop a semiquantitative …
Nitroxide free radicals: spin labels for probing biomolecular structure
OH Griffith, AS Waggoner - Accounts of Chemical Research, 1969 - ACS Publications
Numerous organic molecules havebeen bound to biological macromolecules in efforts to
determine molecular structure and biological function. As early as the 1930’s antibodies and …
determine molecular structure and biological function. As early as the 1930’s antibodies and …
Lipid spin labels in biological membranes
OH Griffith, PC Jost - Spin Labeling Theory and Applications, 1976 - books.google.com
The basic unit of life is the cell. Each living cell is bounded by a thin flexible envelope, the
plasma membrane. The plasma membrane is only a small percentage of the total membrane …
plasma membrane. The plasma membrane is only a small percentage of the total membrane …
Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine
OW Griffith - Analytical biochemistry, 1980 - Elsevier
… All solutions are stable for at least 2 weeks at O”C, although solution (I) often forms a
precipitate which must be redissolved by warming to room temperature. To assay for total …
precipitate which must be redissolved by warming to room temperature. To assay for total …
[HTML][HTML] Potent and specific inhibition of glutathione synthesis by buthionine sulfoximine (Sn-butyl homocysteine sulfoximine).
OW Griffith, A Meister - Journal of Biological Chemistry, 1979 - Elsevier
… sulfoximine thus far studied (Griffith, 0. W., Anderson, ME, and Meister, A. (1979) J. … While
the apparatus was being flushed with nitrogen, the mixture was cooled to O"C, and 2 ~1 of …
the apparatus was being flushed with nitrogen, the mixture was cooled to O"C, and 2 ~1 of …
The genome sequence of the SARS-associated coronavirus
…, SM Coughlin, D Freeman, N Girn, OL Griffith… - Science, 2003 - science.org
We sequenced the 29,751-base genome of the severe acute respiratory syndrome (SARS)–associated
coronavirus known as the Tor2 isolate. The genome sequence reveals that this …
coronavirus known as the Tor2 isolate. The genome sequence reveals that this …