Consumer wearable devices that continuously measure vital signs have been used to monitor
the onset of infectious disease. Here, we show that data from consumer smartwatches can …

Type 2 diabetes mellitus (T2D) is a growing health problem, but little is known about its
early disease stages, its effects on biological processes or the transition to clinical T2D. To …

Precision health relies on the ability to assess disease risk at an individual level, detect early
preclinical conditions and initiate preventive strategies. Recent technological advances in …

Early detection of infectious diseases is crucial for reducing transmission and facilitating
early intervention. In this study, we built a real-time smartwatch-based alerting system that …

Hereditary hearing loss is the most common sensory deficit. We determined that progressive
high-frequency hearing loss in 2 families of Iraqi Jewish ancestry was due to homozygosity …

Age-related hearing loss is due to death over time, primarily by apoptosis, of hair cells in the
inner ear. Studies of mutant genes responsible for inherited progressive hearing loss have …

The large amount of biomedical data derived from wearable sensors, electronic health
records, and molecular profiling (eg, genomics data) is rapidly transforming our healthcare …

Wearable devices digitally measuring vital signs have been used for monitoring health and
illness onset and have high potential for real-time monitoring and disease detection. As such …

The use of genome‐scale sequencing allows for identification of genetic findings beyond
the original indication for testing (secondary findings). The ClinGen Actionability Working …

Exome sequencing is increasingly utilized in both clinical and nonclinical settings, but little
is known about its utility in healthy individuals. Most previous studies on this topic have …