General anesthesia reversibly alters consciousness, without shutting down the brain globally.
Depending on the anesthetic agent and dose, it may produce different consciousness …

Objective Validating objective, brain‐based indices of consciousness in behaviorally
unresponsive patients represents a challenge due to the impossibility of obtaining independent …

… In addition to having been considered at rest, brain activity has also been studied with
different kinds of sensory stimulation using 15 O-radiolabeled water–PET. In passive tasks using …

Consciousness can be defined by two components: arousal (wakefulness) and awareness (subjective
experience). However, neurophysiological consciousness metrics able to …

Survivors of severe brain injuries may end up in a state of ‘wakeful unresponsiveness’ or in
a minimally conscious state. Pharmacological treatments of patients with disorders of …

Background Making an accurate diagnosis in patients with disorders of consciousness remains
challenging. F-fluorodeoxyglucose (FDG)–PET has been validated as a diagnostic tool …

Unresponsive wakefulness syndrome (UWS) patients may retain intact portions of the
thalamocortical system that are spontaneously active and reactive to sensory stimuli but fail to …

Neurophysiological markers can overcome the limitations of behavioural assessments of
Disorders of Consciousness (DoC). EEG alpha power emerged as a promising marker for DoC, …

Background The Perturbational Complexity Index (PCI) was recently introduced to assess
the capacity of thalamocortical circuits to engage in complex patterns of causal interactions. …

Different behavioural signs of consciousness can distinguish patients with an unresponsive
wakefulness syndrome from patients in minimally conscious state (MCS). The Coma …