Recent data show that B cells and plasma cells located in tumours or in tumour-draining
lymph nodes can have important roles in shaping antitumour immune responses. In tumour-…

Photosensitizers are chromophores that generate reactive oxygen species (ROS) upon light
irradiation 1 . They are used for inactivation of specific proteins by chromophore-assisted …

Despite the growing number of immune repertoire sequencing studies, the field still lacks
software for analysis and comprehension of this high-dimensional data. Here we report …

The decrease of TCR diversity with aging has never been studied by direct methods. In this
study, we combined high-throughput Illumina sequencing with unique cDNA molecular …

Deep profiling of antibody and T cell–receptor repertoires by means of high-throughput
sequencing has become an attractive approach for adaptive immunity studies, but its power is …

For understanding the rules and laws of adaptive immunity, high‐throughput profiling of T‐cell
receptor ( TCR ) repertoires becomes a powerful tool. The structure of TCR repertoires is …

Fluorescent proteins with emission wavelengths in the near-infrared and infrared range are
in high demand for whole-body imaging techniques. Here we report near-infrared dimeric …

The phototoxic red fluorescent GFP-like protein KillerRed has recently been described. The
phototoxicity of KillerRed exceeds that of EGFP by at least 1,000-fold, making it the first fully …

High-throughput sequencing has the power to reveal the nature of adaptive immunity as
represented by the full complexity of T-cell receptor (TCR) and antibody (IG) repertoires, but is at …

The TCR repertoire is a mirror of the human immune system that reflects processes caused
by infections, cancer, autoimmunity, and aging. Next generation sequencing (NGS) is …