User profiles for O. T. Schubert
 | Olga T. SchubertGroup Leader at Eawag, lecturer at ETH Zurich Verified email at eawag.ch Cited by 3822 |
Quantitative proteomics: challenges and opportunities in basic and applied research
In this Perspective, we discuss developments in mass-spectrometry-based proteomic
technology over the past decade from the viewpoint of our laboratory. We also reflect on existing …
technology over the past decade from the viewpoint of our laboratory. We also reflect on existing …
OpenSWATH enables automated, targeted analysis of data-independent acquisition MS data
There are amendments to 10.1038/nbt. 2841 220 volume 32 NumBeR 3 mARCH 2014
NATURE BIoTECHNoloGy as Skyline23 and PeakView (AB SCIEX), can visualize the XIC data, …
NATURE BIoTECHNoloGy as Skyline23 and PeakView (AB SCIEX), can visualize the XIC data, …
[HTML][HTML] A repository of assays to quantify 10,000 human proteins by SWATH-MS
… A manuscript providing detailed instructions for the generation of large-scale assay
libraries is in preparation by the authors (Schubert, OT, Gillet, LC, Collins, BC, Navarro, P., …
libraries is in preparation by the authors (Schubert, OT, Gillet, LC, Collins, BC, Navarro, P., …
Building high-quality assay libraries for targeted analysis of SWATH MS data
Targeted proteomics by selected/multiple reaction monitoring (S/MRM) or, on a larger scale,
by SWATH (sequential window acquisition of all theoretical spectra) MS (mass spectrometry…
by SWATH (sequential window acquisition of all theoretical spectra) MS (mass spectrometry…
[PDF][PDF] Genome-wide mapping of transcriptional start sites defines an extensive leaderless transcriptome in Mycobacterium tuberculosis
Deciphering physiological changes that mediate transition of Mycobacterium tuberculosis
between replicating and nonreplicating states is essential to understanding how the pathogen …
between replicating and nonreplicating states is essential to understanding how the pathogen …
The in silico human surfaceome
…, M Müller, OT Schubert… - Proceedings of the …, 2018 - National Acad Sciences
Cell-surface proteins are of great biomedical importance, as demonstrated by the fact that 66%
of approved human drugs listed in the DrugBank database target a cell-surface protein. …
of approved human drugs listed in the DrugBank database target a cell-surface protein. …
[PDF][PDF] Absolute proteome composition and dynamics during dormancy and resuscitation of Mycobacterium tuberculosis
… Schubert et al. develop a strategy to estimate absolute cellular protein concentrations on
a global scale based on the proteomic technique SWATH MS. They use this strategy to …
a global scale based on the proteomic technique SWATH MS. They use this strategy to …
[PDF][PDF] The Mtb proteome library: a resource of assays to quantify the complete proteome of Mycobacterium tuberculosis
Research advancing our understanding of Mycobacterium tuberculosis (Mtb) biology and
complex host-Mtb interactions requires consistent and precise quantitative measurements of …
complex host-Mtb interactions requires consistent and precise quantitative measurements of …
[PDF][PDF] Breast cancer classification based on proteotypes obtained by SWATH mass spectrometry
P Bouchal, OT Schubert, J Faktor, L Capkova… - Cell reports, 2019 - cell.com
Accurate classification of breast tumors is vital for patient management decisions and enables
more precise cancer treatment. Here, we present a quantitative proteotyping approach …
more precise cancer treatment. Here, we present a quantitative proteotyping approach …
From coarse to fine: the absolute Escherichia coli proteome under diverse growth conditions
…, BC Collins, A Schmidt, OT Schubert… - Molecular systems …, 2021 - embopress.org
Accurate measurements of cellular protein concentrations are invaluable to quantitative
studies of gene expression and physiology in living cells. Here, we developed a versatile mass …
studies of gene expression and physiology in living cells. Here, we developed a versatile mass …