We present an extension of the Minimum Information about any (x) Sequence (MIxS) standard
for reporting sequences of uncultivated virus genomes. Minimum Information about an …

Viruses and mobile genetic elements are molecular parasites or symbionts that coevolve
with nearly all forms of cellular life. The route of virus replication and protein expression is …

… VPS4 homologues containing an N-terminal extension. In … We constructed a multiple
alignment of the N-terminal portions … These features, together with the N-terminal localization of …

… moved from C lostridia to a separate class N egativicutes. However, draft genome sequences
of the spore‐forming members of the N egativicutes revealed typically clostridial sets of …

Giant viruses such as Mimivirus isolated from amoeba found in aquatic habitats show
biological sophistication comparable to that of simple cellular life forms and seem to evolve by …

… each of them (N 1 and N 2 ) as well as the number of NCVOGs present in both (N U ) were …
was calculated as either s = N U /min(N 1 , N 2 ) or s = N U /sqrt(N 1 × N 2 ) and converted to a …

Small, hydrophobic proteins whose synthesis is repressed by small RNAs (sRNAs), denoted
type I toxin–antitoxin modules, were first discovered on plasmids where they regulate …

The discovery of giant viruses blurred the sharp division between viruses and cellular life.
Giant virus genomes encode proteins considered as signatures of cellular organisms, …

… Natalya Yutin and Eugene V. Koonin are supported by intramural funds of the US Department
of Health and Human Services (to the National Library of Medicine). James Van Etten is …

Metagenomic sequence analysis is rapidly becoming the primary source of virus discovery
1 , 2 – 3 . A substantial majority of the currently available virus genomes come from …