User profiles for N. Weisenfeld
Neil I. WeisenfeldStaff Scientist, 10x Genomics, Inc. Verified email at 10xgenomics.com Cited by 6307 |
Schizophrenia is associated with elevated amphetamine-induced synaptic dopamine concentrations: evidence from a novel positron emission tomography method
…, DR Weinberger, N Weisenfeld… - Proceedings of the …, 1997 - National Acad Sciences
A major line of evidence that supports the hypothesis of dopamine overactivity in schizophrenia
is the psychomimetic potential of agents such as amphetamine that stimulate dopamine …
is the psychomimetic potential of agents such as amphetamine that stimulate dopamine …
A single-cell and spatially resolved atlas of human breast cancers
Breast cancers are complex cellular ecosystems where heterotypic interactions play central
roles in disease progression and response to therapy. However, our knowledge of their …
roles in disease progression and response to therapy. However, our knowledge of their …
Direct determination of diploid genome sequences
… Assemblies have been deposited at DDBJ/ENA/GenBank (https://www.ncbi.nlm.gov/genbank/)
under the accessions MSBx000 00000 where x is in {J,K,L,M,N,O,P}, and the versions …
under the accessions MSBx000 00000 where x is in {J,K,L,M,N,O,P}, and the versions …
Association of ketamine-induced psychosis with focal activation of the prefrontal cortex in healthy volunteers.
…, AK Malhotra, DA Pinals, NI Weisenfeld… - The American journal …, 1997 - europepmc.org
Objective Agents that antagonize the N-methyl-D-aspartic acid (NMDA) receptor, such as
phencyclidine and ketamine, produce an acute psychotic state in normal individuals that …
phencyclidine and ketamine, produce an acute psychotic state in normal individuals that …
[HTML][HTML] NIDCAP improves brain function and structure in preterm infants with severe intrauterine growth restriction
…, SC Butler, L Lightbody, S Kosta, NI Weisenfeld… - Journal of …, 2012 - nature.com
… processes underlying NIDCAP effectiveness are speculative, which is a serious limitation
of the study: NIDCAP may reduce iatrogenic NICU damage by resetting the NMDA (N-methyl-D…
of the study: NIDCAP may reduce iatrogenic NICU damage by resetting the NMDA (N-methyl-D…
[HTML][HTML] A spatially resolved brain region-and cell type-specific isoform atlas of the postnatal mouse brain
…, B Haase, A Hayes, JG Chew, NI Weisenfeld… - Nature …, 2021 - nature.com
Splicing varies across brain regions, but the single-cell resolution of regional variation is
unclear. We present a single-cell investigation of differential isoform expression (DIE) between …
unclear. We present a single-cell investigation of differential isoform expression (DIE) between …
[PDF][PDF] Dissecting the causal mechanism of X-linked dystonia-parkinsonism by integrating genome and transcriptome assembly
…, D Henderson, N Ito, N Weisenfeld, D Jaffe, N Sharma… - Cell, 2018 - cell.com
… the probands for whom the age of disease onset could be determined (n = 303). A subset
of these probands (n = 263) were able to provide further clinical information about the pattern …
of these probands (n = 263) were able to provide further clinical information about the pattern …
Comprehensive variation discovery in single human genomes
NI Weisenfeld, S Yin, T Sharpe, B Lau, R Hegarty… - Nature …, 2014 - nature.com
Complete knowledge of the genetic variation in individual human genomes is a crucial
foundation for understanding the etiology of disease. Genetic variation is typically characterized …
foundation for understanding the etiology of disease. Genetic variation is typically characterized …
Automatic segmentation of newborn brain MRI
NI Weisenfeld, SK Warfield - Neuroimage, 2009 - Elsevier
Quantitative brain tissue segmentation from newborn MRI offers the possibility of improved
clinical decision making and diagnosis, new insight into the mechanisms of disease, and new …
clinical decision making and diagnosis, new insight into the mechanisms of disease, and new …
Capturing intraoperative deformations: research experience at Brigham and Women's Hospital
…, SJ Haker, IF Talos, CA Kemper, N Weisenfeld… - Medical image …, 2005 - Elsevier
… Hence the interpolating function of node i of tetrahedral element e is defined as N i e ( x ) = 1
6 … We define the matrix B i e = L N i e at each node of each element, and since the energy of …
6 … We define the matrix B i e = L N i e at each node of each element, and since the energy of …