Metabolite levels together with their corresponding metabolic fluxes are integrative
outcomes of biochemical transformations and regulatory processes and they can be used to …

The existence of Metabolic Gene Clusters (MGCs) in plant genomes has recently raised
increased interest. Thus far, MGCs were commonly identified for pathways of specialized …

… In this study, we considered the metabolism of a mature source leaf under field conditions
(ie, a metabolic system that functions to assimilate C and N and to synthesize sugars and …

Our previous studies have demonstrated that atorvastatin induces autophagy in the
androgen receptor negative prostate cancer PC3 cells through inhibition of geranylgeranyl …

The availability of multi-omics data sets and genome-scale metabolic models for various
organisms provide a platform for modeling and analyzing genotype-to-phenotype relationships. …

The green alga Hematococcus pluvialis accumulates large amounts of the antioxidant
astaxanthin under inductive stress conditions, such as nitrogen starvation. The response to …

Rationale: Human induced pluripotent stem cell–derived cardiomyocytes (hiPSC-CMs) in
combination with CRISPR/Cas9 genome editing provide unparalleled opportunities to study …

Current innovations in mass‐spectrometry‐based technologies allow deep coverage of protein
expression. Despite its immense value and in contrast to transcriptomics, only a handful …

Background: Cancer therapy–induced cardiomyopathy (CCM) is associated with cumulative
drug exposures and preexisting cardiovascular disorders. These parameters incompletely …

Introduction: Long-term outcomes are of particular importance in evaluating interventions for
family caregivers of people with dementia (PwD). So far, evidence for long-term effects (> 6 …