User profiles for N. Satani

Nikunj Satani

Assistant Professor, Vascular Neurology, The University of Texas Health Science Center at …
Verified email at uth.tmc.edu
Cited by 2781

The intricate mechanisms of neurodegeneration in prion diseases

C Soto, N Satani - Trends in molecular medicine, 2011 - cell.com
Prion diseases are a group of infectious neurodegenerative diseases with an entirely novel
mechanism of transmission, involving a protein-only infectious agent that propagates the …

[PDF][PDF] Tumor evolution of glioma-intrinsic gene expression subtypes associates with immunological changes in the microenvironment

…, S Lyu, P Li, Y Li, F Barthel, HJ Cho, YH Lin, N Satani… - Cancer cell, 2017 - cell.com
We leveraged IDH wild-type glioblastomas, derivative neurospheres, and single-cell gene
expression profiles to define three tumor-intrinsic transcriptional subtypes designated as …

[HTML][HTML] Mesenchymal stem cell derived extracellular vesicles for repairing the neurovascular unit after ischemic stroke

C Davis, SI Savitz, N Satani - Cells, 2021 - mdpi.com
Ischemic stroke is a debilitating disease and one of the leading causes of long-term
disability. During the early phase after ischemic stroke, the blood-brain barrier (BBB) exhibits …

Genomic deletion of malic enzyme 2 confers collateral lethality in pancreatic cancer

…, A Chen, T Gutschner, Y Kang, J Fleming, N Satani… - Nature, 2017 - nature.com
… PDAC TCGA copy-number and transcriptomic analyses (n = 185) and a study of microdissected
PDAC samples (n = 109) 7 have revealed homozygous deletion of SMAD4 in 14% (25 …

Tumor evolution of glioma-intrinsic gene expression subtypes associates with immunological changes in the microenvironment

…, S Lyu, P Li, Y Li, F Barthel, HJ Cho, YH Lin, N Satani… - Cancer cell, 2018 - cell.com
In the originally published version of this paper’s Supplemental Information, incorrect
headers were used for the gene signatures listed in Table S1. Specifically, the headers of the …

[HTML][HTML] World-wide efficacy of bone marrow derived mesenchymal stromal cells in preclinical ischemic stroke models: systematic review and meta-analysis

N Satani, C Cai, K Giridhar, D McGhiey… - Frontiers in …, 2019 - frontiersin.org
… more pronounced in studies from Asia as compared with North America (p = 0.04, Table 2). …
higher effect size as compared to studies in North America. To provide current up to date …

[HTML][HTML] HSP90 inhibition enhances cancer immunotherapy by upregulating interferon response genes

…, AH Talukder, SC Tripathi, H Khong, N Satani… - Nature …, 2017 - nature.com
… A library of 850 bioactive compounds was curated by Florian Mueller and Nikunj Satani (MDACC)
and purchased from Selleckchem. A total of 50,000 patient derived human melanoma …

SF2312 is a natural phosphonate inhibitor of enolase

…, N Satani, D Maxwell, YH Lin, N Hammoudi… - Nature chemical …, 2016 - nature.com
… To be consistent with the numbering in previous ENO2-related publications, we
numbered residues starting from serine (instead of the N-terminal methionine, which is post-…

An enolase inhibitor for the targeted treatment of ENO1-deleted cancers

YH Lin, N Satani, N Hammoudi, VC Yan… - Nature …, 2020 - nature.com
… as a percentage of CT (n = 2 (CT), mean of n = 1 (treated biological … as a percentage of
CT (n = 4 (CT), mean of n = 2 (treated … as a percentage of CT (n = 4 (CT), mean of n = 2 (treated …

The effect of topoisomerase I inhibitors on the efficacy of T-cell-based cancer immunotherapy

…, C Haymaker, C Bernatchez, N Satani… - JNCI: Journal of the …, 2018 - academic.oup.com
… had greater postaccession survival (n = 84 patients; mean = 97.6 months, 95% CI = 65.3 to
N/A) in comparison with patients with low TP53INP1 expression (n = 84 patients; mean = 64.2 …