[HTML][HTML] The genomes of four tapeworm species reveal adaptations to parasitism

…, J Parkinson, N Pouchkina-Stantcheva, N Riddiford… - Nature, 2013 - nature.com
Tapeworms (Cestoda) cause neglected diseases that can be fatal and are difficult to treat,
owing to inefficient drugs. Here we present an analysis of tapeworm genome sequences using …

Functional divergence of former alleles in an ancient asexual invertebrate

NN Pouchkina-Stantcheva, BM McGee, C Boschetti… - Science, 2007 - science.org
Theory suggests it should be difficult for asexual organisms to adapt to a changing environment
because genetic diversity can only arise from mutations accumulating within direct …

Foreign genes and novel hydrophilic protein genes participate in the desiccation response of the bdelloid rotifer Adineta ricciae

C Boschetti, N Pouchkina-Stantcheva… - Journal of …, 2011 - journals.biologists.com
… their lack of non-reducing disaccharides, the bdelloid LEA proteins defined to date are
not especially hydrophilic and can exhibit secondary structure in solution (Pouchkina-Stantcheva

Spliced Leader RNA–Mediated trans-Splicing in Phylum Rotifera

NN Pouchkina-Stantcheva… - Molecular biology and …, 2005 - academic.oup.com
In kinetoplastids, Euglena, and four metazoan phyla, trans-splicing has been described as a
mechanism for the generation of mature messenger RNAs (mRNAs): 5′-ends of precursor …

[HTML][HTML] The protein subunit of telomerase displays patterns of dynamic evolution and conservation across different metazoan taxa

AG Lai, N Pouchkina-Stantcheva… - BMC evolutionary …, 2017 - Springer
… -terminal linker is unclear beyond vertebrates, it is apparent that the linker sequence can
provide additional surface areas to allow conformational flexibility between the N-terminus and …

RNA-mediated gene suppression and in vitro culture in Hymenolepis microstoma

NN Pouchkina-Stantcheva, LJ Cunningham… - International journal for …, 2013 - Elsevier
Hymenolepis microstoma, the mouse bile-duct tapeworm, is a classical rodent-hosted model
that provides easy laboratory access to all stages of the life cycle. Recent characterisation …

Transient expression of a major ampullate spidroin 1 gene fragment from Euprosthenops sp. in mammalian cells

…, N Pouchkina-Stantcheva… - Cancer Genomics & …, 2006 - cgp.iiarjournals.org
Spider silk possesses extraordinary and unsurpassed mechanical properties and several
attempts have been made to artificially produce spider silk in order to manufacture strong and …

Molecular studies of a novel dragline silk from a nursery web spider, Euprosthenops sp.(Pisauridae)

NN Pouchkina-Stantcheva… - … and Physiology Part B …, 2004 - Elsevier
Various spider species produce dragline silks with different mechanical properties. The primary
structure of silk proteins is thought to contribute to the elasticity and strength of the fibres. …

Spatial and temporal consistency of putative reference genes for real-time PCR in a model tapeworm

NN Pouchkina-Stantcheva, LJ Cunningham… - Molecular and …, 2011 - Elsevier
Relative quantification of gene expression by real-time PCR relies on the use of reference
genes whose expressed levels remain consistent across experimental conditions. Here we …

Analyses of the core eukaryotic protein subunit of telomerase support extensive adaptation to different evolutionary and life histories in the Metazoa

AG Lai, N Pouchkina-Stantcheva, A Di Donfrancesco… - bioRxiv, 2016 - biorxiv.org
… with intact CTE or N-terminal linker regions for comparison. Although we failed to compare
N-termini of parasitic flatworms, we were able to identify planarian-specific N-terminal motifs …