User profiles for N. Papili Gao

Nan Papili Gao

PhD student, ETH Zurich
Verified email at ethz.ch
Cited by 479

[HTML][HTML] Single-cell-based analysis highlights a surge in cell-to-cell molecular variability preceding irreversible commitment in a differentiation process

…, V Morin, E Vallin, A Guillemin, N Papili Gao… - PLoS …, 2016 - journals.plos.org
… The I score was calculated as previously described in [51] as follows: among the n = 90
studied genes, we defined a subset D containing n D genes. We then defined the I score as: with …

SINCERITIES: inferring gene regulatory networks from time-stamped single cell transcriptional expression profiles

N Papili Gao, SMM Ud-Dean, O Gandrillon… - …, 2018 - academic.oup.com
… the n-2 vector of D D ^ distances of gene j corresponding to time windows Δt 2 to Δt n- 1 ,
and X denotes the (n-2)×m matrix of D D ^ distances corresponding to time windows Δt 1 to Δt n

[HTML][HTML] Glycosylation flux analysis of immunoglobulin G in chinese hamster ovary perfusion cell culture

S Hutter, M Wolf, N Papili Gao, D Lepori, T Schweigler… - Processes, 2018 - mdpi.com
… The N-linked glycosylation of mAbs has been shown to … been proposed to study the N-linked
glycosylation process based … In this study, we applied the improved GFA to analyze the N-…

[HTML][HTML] Global genome decompaction leads to stochastic activation of gene expression as a first step toward fate commitment in human hematopoietic cells

…, S Chantalat, R Sudharshan, N Papili Gao… - PLoS …, 2022 - journals.plos.org
… However, during this period, the total number of DE genes is much lower (n = 1,849)
compared to the 5-h to 24-h period (n = 6,230) and statistical tests did not reveal any significant …

[HTML][HTML] CALISTA: clustering and LINEAGE inference in single-cell transcriptional analysis

N Papili Gao, T Hartmann, T Fang… - … in bioengineering and …, 2020 - frontiersin.org
… into a N × G matrix, where G denotes the number of genes, N denotes the number of cells,
and the matrix element m n,g is the transcriptional expression value of gene g in the n-th cell. …

Constraints on human CD34+ cell fate due to lentiviral vectors can be relieved by valproic acid

A Moussy, N Papili Gao, G Corre, V Poletti… - Human gene …, 2019 - liebertpub.com
The initial stages following the in vitro cytokine stimulation of human cord blood CD34+
cells overlap with the period when lentiviral gene transfer is typically performed. Single-cell …

Selective silencing rather than targeted activation of gene expression underlies fate choice in human hematopoietic stem cells

…, S Chantalat, L Racine, R Sudharshan, N Papili Gao… - bioRxiv, 2020 - biorxiv.org
When human cord blood derived CD34+ cells are induced to differentiate in vitro, they
undergo rapid and dynamic morphological and molecular transformation that are critical for the …

[HTML][HTML] Single-cell transcriptional uncertainty landscape of cell differentiation

NP Gao, O Gandrillon, A Páldi, U Herbach… - …, 2023 - ncbi.nlm.nih.gov
… , denoted by NLL n , is the sum of the NLL from every gene g for that cell, ie NLL n = ∑ g =
1 N g NLL g n where N g … Using the CALISTA method that they have developed, Papili Gao

Universality of cell differentiation trajectories revealed by a reconstruction of transcriptional uncertainty landscapes from single-cell transcriptomic data

NP Gao, O Gandrillon, A Páldi, U Herbach, R Gunawan - bioRxiv, 2020 - biorxiv.org
… Given an N × G single-cell expression matrix M, where N denotes the number of cells and G
… of the expression data m n,g – ie the number of transcripts of gene g in the n-th cell, and a …

Analysis of single-cell transcriptional profiles

N Papili Gao - 2019 - research-collection.ethz.ch
… NAN PAPILI GAO … form: 𝐲 = 𝐗𝛂, where y denotes the n-2 vector of 𝐷𝐷 distances of gene j
corresponding to time windows Δt2 to Δtn-1, and X denotes the (n2)×m matrix of 𝐷𝐷 distances …