… The upper bound on the growth rate maximization occurs when the translation efficiency κ
t and the nutritional efficiency κ n are both maximum for a given nutrient environment. Figure …

… in 200 μL fresh M9 glucose supplemented with 200 nM colicin N 1-185 PAmCherry [expressed
and purified in the same manner as colicin N 1-185 mCherry (29)], and labeling of OmpF …

The actomyosin contractile ring assembles through the condensation of a broad band of
nodes that forms at the cell equator in fission yeast cytokinesis. The condensation process …

10.7554/eLife.47033.001 Rod-shaped bacterial cells can readily adapt their lengths and
widths in response to environmental changes. While many recent studies have focused on the …

Bacteria have evolved to develop multiple strategies for antibiotic resistance by effectively
reducing intracellular antibiotic concentrations or antibiotic binding affinities, but the role of cell …

… We simulate the stochastic growth and shape dynamics of a total of n = 40 cells, for g =
100 generations each (Figs. 3,4). We initialize the shape of cell j (1 ≤ j ≤ n) by prescribing its …

… maximum growth rate characteristic of the medium, and n à is the value of ―n when
kspecific/k0 = 0.5. When the nutrients inside the cell reach saturation, ie, d―n /dt = 0, we have k = …

… Assuming that n increases proportionally to the CIP concentration (c), we would then
expect a concave relationship between the net growth rate (birth minus death) and c, with a …

10.7554/eLife.18657.001 When starved, the Gram-positive bacterium Bacillus subtilis forms
durable spores for survival. Sporulation initiates with an asymmetric cell division, creating a …

The means by which the physicochemical properties of different cellular components
together determine bacterial cell shape remain poorly understood. Here, we investigate a …