Cell-free DNA in the blood provides a non-invasive diagnostic avenue for patients with
cancer 1 . However, characteristics of the origins and molecular features of cell-free DNA are …

Immune checkpoint inhibitors have shown significant therapeutic responses against tumors
containing increased mutation-associated neoantigen load. We have examined the evolving …

Through exomic sequencing of 32 intrahepatic cholangiocarcinomas, we discovered frequent
inactivating mutations in multiple chromatin-remodeling genes (including BAP1, ARID1A …

… are as follows: stage I n = 15, II n = 7, III n = 35, IV n = 72; and individuals in the cohort with
lung adenocarcinoma comprised stage I n = 8, II n = 3, III n = 14, IV n = 37. The points colored …

… and the length of the cell cycle is constant, the number of somatic mutations in the metastasis
cell that were present in the STIC follows a binomial distribution with parameters n k and …

Background & Aims The management of pancreatic cysts poses challenges to both patients
and their physicians. We investigated whether a combination of molecular markers and …

… We represent the occurrences of each context in the entire protein coding sequence by N i
, and in each gene of interest by g i . Subsequently, we identify the dinucleotide context for all …

Background Neoadjuvant anti-PD-1 may improve outcomes for patients with resectable
NSCLC and provides a critical window for examining pathologic features associated with …

This paper reviews current work from our group on the mechanism of droplet break-up and
coalescence. In order to do this a reflectance technique was used to measure the rate of …

Tumor mutation burden is an imperfect proxy of tumor foreignness and has therefore failed
to consistently demonstrate clinical utility in predicting responses in the context of …