… three guanines per run, separated by other bases (N). G4 motifs confer the ability to form a
… diagram of two possible conformations formed by the G4 motif G 3 N 3 G 3 N 2 G 4 N 2 G 5 . …

Recent advances have made a persuasive case for the existence of G4 DNA in living cells,
but what—if any—are its functions? Experiments have established how G4 DNA may …

Three processes alter genomic sequence and structure at the immunoglobulin genes of B
lymphocytes: gene conversion, somatic hypermutation, and class switch recombination. …

BLM, the gene that is defective in Bloom's syndrome, encodes a protein homologous to RecQ
subfamily helicases that functions as a 3′-5′ DNA helicase in vitro. We now report that …

We show that intracellular transcription of G-rich regions produces novel DNA structures,
visible by electron microscopy as large (150–500 bp) loops. These G-loops are formed …

G-rich genomic regions can form G4 DNA upon transcription or replication. We have
quantified the potential for G4 DNA formation (G4P) of the 16 654 genes in the human RefSeq …

… Anti-hnRNP D antibodies were raised against peptide CMSEEQFGGDG, which corresponds
to the N terminus of both human and murine hnRNP D (21), with a cysteine added to …

Single-stranded RNA viruses often have 3'-terminal tRNA-like structures that serve as
substrates for the enzymes of tRNA metabolism, including the tRNA synthases and the CCA-…

To understand how potential for G-quadruplex formation might influence regulation of gene
expression, we examined the 2 kb spanning the transcription start sites (TSS) of the 18 217 …

… The G ≥3 N x G ≥3 N x G ≥3 N x G ≥3 sequence motif constitutes a loose rather than
strict consensus. Some sequences that do not strictly conform to the consensus do form …