The BioPAX community standard for pathway data sharing

…, S Goto, M Hucka, N Le Novère, N Maltsev… - Nature …, 2010 - nature.com
Biological Pathway Exchange (BioPAX) is a standard language to represent biological
pathways at the molecular and cellular level and to facilitate the exchange of pathway data. The …

A consensus yeast metabolic network reconstruction obtained from a community approach to systems biology

…, M Heinemann, M Hucka, N Le Novere… - Nature …, 2008 - nature.com
Genomic data allow the large-scale manual or semi-automated assembly of metabolic
network reconstructions, which provide highly curated organism-specific knowledge bases. …

International Union of Pharmacology. XX. Current status of the nomenclature for nicotinic acetylcholine receptors and their subunits

RJ Lukas, JP Changeux, N le Novère… - Pharmacological …, 1999 - ASPET
… The features of these integral membrane proteins include an extensive N-terminal region
positioned extracellularly, four transmembrane segments (M1–M4), an extended cytoplasmic …

The systems biology markup language (SBML): a medium for representation and exchange of biochemical network models

…, A Kremling, U Kummer, N Le Novère… - …, 2003 - academic.oup.com
Motivation: Molecular biotechnology now makes it possible to build elaborate systems
models, but the systems biology community needs information standards if models are to be …

A community-driven global reconstruction of human metabolism

…, N Juty, S Keating, I Nookaew, N Le Novère… - Nature …, 2013 - nature.com
Multiple models of human metabolism have been reconstructed, but each represents only a
subset of our knowledge. Here we describe Recon 2, a community-driven, consensus '…

BioModels Database: a free, centralized database of curated, published, quantitative kinetic models of biochemical and cellular systems

N Le Novere, B Bornstein, A Broicher… - Nucleic acids …, 2006 - academic.oup.com
BioModels Database ( http://www.ebi.ac.uk/biomodels/ ), part of the international initiative
BioModels.net, provides access to published, peer-reviewed, quantitative models of …

[HTML][HTML] BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models

…, MI Stefan, JL Snoep, M Hucka, N Le Novère… - BMC systems …, 2010 - Springer
… Nicolas Le Novère … Faster access for North American users is provided through a mirror at
the … Le Novère N, Bornstein B, Broicher A, Courtot M, Donizelli M, Dharuri H, Li L, Sauro H, …

Subunit composition of functional nicotinic receptors in dopaminergic neurons investigated with knock-out mice

…, M Moretti, FM Rossi, N Le Novere… - Journal of …, 2003 - Soc Neuroscience
… Only neurons exhibiting a stable response were then bath perfused with the nicotinic
antagonists αCtxMII (100 nm) and/or methyllycaconitine (MLA; 1 nm). ACh pulses were …

Molecular evolution of the nicotinic acetylcholine receptor: an example of multigene family in excitable cells

N Le Novere, JP Changeux - Journal of molecular evolution, 1995 - Springer
An extensive phylogenetic analysis of the nicotinic-acetylcholine-receptor subunit gene
family has been performed by cladistic and phenetic methods. The conserved parts of amino …

The diversity of subunit composition in nAChRs: evolutionary origins, physiologic and pharmacologic consequences

N Le Novere, PJ Corringer… - Journal of …, 2002 - Wiley Online Library
… have been divided in four subfamilies in vertebrates (Le Nove`re and Changeux, 1995;
Ortells and … Desensitization of neuronal nicotinic acetylcholine receptors conferred by nterminal …