Alcohol drinking, cigarette smoking, and the development of squamous cell carcinoma of the esophagus: epidemiology, clinical findings, and prevention

M Morita, R Kumashiro, N Kubo, Y Nakashima… - International journal of …, 2010 - Springer
Both cigarette smoking and alcohol drinking are well-established risk factors for esophageal
squamous cell carcinoma (ESCC), and the relationship of dose to cancer risk has already …

[HTML][HTML] Cancer-associated fibroblasts in hepatocellular carcinoma

N Kubo, K Araki, H Kuwano… - World journal of …, 2016 - ncbi.nlm.nih.gov
The hepatic stellate cells in the liver are stimulated sustainably by chronic injury of the
hepatocytes, activating myofibroblasts, which produce abundant collagen. Myofibroblasts are the …

[HTML][HTML] Current status in remnant gastric cancer after distal gastrectomy

M Ohira, T Toyokawa, K Sakurai, N Kubo… - World journal of …, 2016 - ncbi.nlm.nih.gov
Remnant gastric cancer (RGC) and gastric stump cancer after distal gastrectomy (DG) are
recognized as the same clinical entity. In this review, the current knowledges as well as the …

The complete sequence of the rice (Oryza sativa L.) mitochondrial genome: frequent DNA sequence acquisition and loss during the evolution of flowering plants

Y Notsu, S Masood, T Nishikawa, N Kubo… - Molecular genetics and …, 2002 - Springer
The entire mitochondrial genome of rice (Oryza sativa L.), a monocot plant, has been
sequenced. It was found to comprise 490,520 bp, with an average G+C content of 43.8%. Three …

Overexpression of interleukin-10 by activated T lymphocytes inhibits atherosclerosis in LDL receptor–deficient mice by altering lymphocyte and macrophage …

…, G Subbanagounder, MC Fishbein, N Kubo… - Circulation …, 2002 - Am Heart Assoc
… The recipient mice received bone marrow from either WT (n=10) or IL-10 Tg (n=9) mice. After
BMT, mice were fed chow diet (No. 5015) for 4 weeks, and blood was obtained for baseline …

Promoter-proximal CTCF binding promotes distal enhancer-dependent gene activation

N Kubo, H Ishii, X Xiong, S Bianco… - Nature structural & …, 2021 - nature.com
The CCCTC-binding factor (CTCF) works together with the cohesin complex to drive the
formation of chromatin loops and topologically associating domains, but its role in gene …

Mutations in a TGF-β Ligand, TGFB3, Cause Syndromic Aortic Aneurysms and Dissections

…, K Minatoya, R Matsukawa, T Tsukube, N Kubo… - Journal of the American …, 2015 - jacc.org
… In addition, hydrophobic contacts with the N-terminal helix in the LAP domain will be
affected by the substitution with threonine (hydrophilic). Substitution from Leu401 to proline is …

A novel locus for clubroot resistance in Brassica rapa and its linkage markers

M Hirai, T Harada, N Kubo, M Tsukada… - Theoretical and applied …, 2004 - Springer
… The CR inbred parental line N-WMR-3 used in this study was obtained by crossing the …
only the most effective CR locus remains in N-WMR-3. Therefore, Crr3 in N-WMR-3 is thought to …

Clinical implications of provocation tests for coronary artery spasm: safety, arrhythmic complications, and prognostic impact: multicentre registry study of the Japanese …

…, S Sueda, T Sato, S Ogawa, N Kubo… - European heart …, 2013 - academic.oup.com
… (n = 99) or were diagnosed based on spontaneous attack alone without a provocation test (n
= 185)… tests, including retrospective (n = 1106) and prospective populations (n = 138), were …

Prognostic stratification of patients with vasospastic angina: a comprehensive clinical risk score developed by the Japanese Coronary Spasm Association

…, Y Tanabe, S Sueda, T Sato, S Ogawa, N Kubo… - Journal of the American …, 2013 - jacc.org
… According to the total score in individual patients, 3 risk strata were defined; low (score 0
to 2, n = 598), intermediate (score 3 to 5, n = 639) and high (score 6 or more, n = 192). The …