The glutathione status of cells

NS Kosower, EM Kosower - International review of cytology, 1978 - Elsevier
Publisher Summary Glutathione (GSH) is the most important nonprotein thiol in living
systems and is of widespread occurrence in the intracellular milieu of animals, plants, and …

Environment dominates over host genetics in shaping human gut microbiota

…, N Zmora, M Pevsner-Fischer, D Israeli, N Kosower… - Nature, 2018 - nature.com
Human gut microbiome composition is shaped by multiple factors but the relative contribution
of host genetics remains elusive. Here we examine genotype and microbiome data from …

[PDF][PDF] Personalized nutrition by prediction of glycemic responses

…, J Suez, JA Mahdi, E Matot, G Malka, N Kosower… - Cell, 2015 - cell.com
… Sampling was done using a swab (n = 776) or both a swab and an OMNIgeneGUT (OMR-200;
DNA Genotek… ES is supported by a research grant from Jack N. Halpern, and Mr. and Mrs. …

[11] Diamide: An oxidant probe for thiols

NS Kosower, EM Kosower - Methods in enzymology, 1995 - Elsevier
… The most convenient and chemically simple agent was diazenedicarboxylic acid bis(N,N-dimethylamide),
now known by the trivial name, diamide. 1 Diamide is commercially available …

Diamide, a new reagent for the intracellular oxidation of glutathione to the disulfide

NS Kosower, EM Kosower, B Wertheim… - … and biophysical research …, 1969 - Elsevier
… The compound is diazenedicarboxylic acid bis(N, N-dimethylamide), II, for which we prefer
the trivial name, diamide. Diamide is easily made by the eynthesis of Crawford and coworkers …

A reference map of potential determinants for the human serum metabolome

…, D Zeevi, D Rothschild, S Leviatan, N Kosower… - Nature, 2020 - nature.com
… We performed genome-wide associations for single metabolites (n = 1,170) and calculated
the P value and the estimated effect sizes using plink (v.1.07). When declaring a genome-…

Bimane fluorescent labels: labeling of normal human red cells under physiological conditions.

NS Kosower, EM Kosower… - Proceedings of the …, 1979 - National Acad Sciences
The bimane fluorescent labels, monobromobimane, dibromobimane, and
monobromotrimethylammoniobimane, are derivatives of syn-9,10-dioxabimane:1,5-diazabicyclo[3.3.0]octa-3,6-…

[PDF][PDF] Bread affects clinical parameters and induces gut microbiome-associated personal glycemic responses

…, N Bar, M Lotan-Pompan, T Avnit-Sagi, N Kosower… - Cell metabolism, 2017 - cell.com
Bread is consumed daily by billions of people, yet evidence regarding its clinical effects is
contradicting. Here, we performed a randomized crossover trial of two 1-week-long dietary …

Personalized postprandial glucose response–targeting diet versus mediterranean diet for glycemic control in prediabetes

…, T Travinsky Shmul, BC Wolf, N Kosower… - Diabetes …, 2021 - Am Diabetes Assoc
… We randomly assigned adults with prediabetes (n = 225) to follow a MED diet or a PPT diet
for a 6-month dietary intervention and additional 6-month follow-up. The PPT diet relies on a …

Thiol‐disulfide status and acridine orange fluorescence of mammalian sperm nuclei

NS KOSOWER, H KATAYOSE… - Journal of …, 1992 - Wiley Online Library
The relationship between thiol‐disulfide status and acridine orange fluorescence of testicular,
epididymal, and ejaculated spermatozoa in several mammalian species was investigated. …