Acidosis predicts mortality independently from hyperlactatemia in patients with sepsis

B Wernly, N Heramvand, M Masyuk, R Rezar… - European journal of …, 2020 - Elsevier
Rationale and objectives Acidosis and hyperlactatemia predict outcome in critically ill patients.
We assessed BE and pH for risk prediction capabilities in a sub-group of septic patients in …

[HTML][HTML] Elevated initial serum phosphate levels predict higher mortality and impaired neurological outcome in cardiac arrest patients with return of spontaneous …

…, M Ortkemper, C Quast, F Voß, N Heramvand… - Diagnostics, 2023 - mdpi.com
… Overall, approximately two-thirds of the patients from the analyzed collective died during
hospitalization (n = 340, 70%), whereas the other third survived to discharge (n = 148, 30%). …

Relevance of pre-existing anaemia for patients admitted for acute coronary syndrome to an intensive care unit: a retrospective cohort analysis of 7418 patients

…, R Rezar, M Cramer, N Heramvand… - … Heart Journal Open, 2022 - academic.oup.com
Aims Patients with acute coronary syndrome (ACS) frequently suffer from anaemia, but its
role in patients admitted to an intensive care unit (ICU) is unclear. This analysis evaluates the …

[HTML][HTML] Experimental noise cutoff boosts inferability of transcriptional networks in large-scale gene-deletion studies

CF Blum, N Heramvand, AS Khonsari… - Nature …, 2018 - nature.com
Generating a comprehensive map of molecular interactions in living cells is difficult and
great efforts are undertaken to infer molecular interactions from large-scale perturbation …

[HTML][HTML] Pharmacosimulation of delays and interruptions during administration of tirofiban: a systematic comparison between EU and US dosage regimens

N Heramvand, M Masyuk, JM Muessig, AM Nia… - Journal of thrombosis …, 2022 - Springer
Tirofiban is a glycoproteine (GP) IIb/IIIa receptor antagonist, which inhibits platelet-platelet
aggregation and is a potential adjunctive antithrombotic treatment in patients with acute …

[PDF][PDF] Merits and Limits of Biological Systems Modeling Strategies

N Heramvand - 2023 - docserv.uni-duesseldorf.de
… CF Blum and N. Heramvand contributed equally to this work. Correspondence and
requests for materials should be addressed to MK (email: markus.kollmann@hhu.de) …

Inferability of transcriptional networks from large scale gene deletion studies

CF Blum, N Heramvand, AS Khonsari, M Kollmann - bioRxiv, 2016 - biorxiv.org
… situation that a significant amount of interactions within an N-gene network are non-inferable, …
constraints, we consider a directed network of N nodes, with node activities as observables …

Testing House of God's Law VII: Was the Fat Man Right?

B Wernly, N Heramvand, M Mirna… - Journal of Intensive …, 2020 - journals.sagepub.com
In Stephen Bergman’s 1978 best-selling novel The House of God, the author describes the
ups and downs in the health care system from the point of view of a young resident in training …

Pharmacosimulation of interruptions and its solution in intravenous administration of cangrelor

M Masyuk, N Heramvand, JM Muessig… - Clinical …, 2018 - content.iospress.com
BACKGROUND: Cangrelor is an intravenous adenosine diphosphate (ADP) P2Y 12
receptor antagonist, which has to be administered as a bolus followed by immediate infusion. …

Webinar| Characterizing cancers from liquid biopsies and FFPE samples: The rise of targeted sequencing panels AUDIO

PM Williams, JP Segal - Science, 2016 - science.org
The detection of cancer in the body, particularly early in its progression, can provide life-saving
information for subsequent treatment. Researchers are now demonstrating that increases …